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Revisions in the International System for Staging Lung Cancer
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Abstract
Revisions in stage grouping of the TNM subsets (T=primary tumor, N=regional lymph
nodes, M=distant metastasis) in the International System for Staging Lung Cancer have
been adopted by the American Joint Committee on Cancer and the Union Internationale
Contre le Cancer. These revisions were made to provide greater specificity for identifying
patient groups with similar prognoses and treatment options with the least disruption
of the present classification: T1N0M0, stage IA; T2N0M0, stage IB; T1N1M0, stage IIA;
T2N1M0 and T3N0M0, stage IIB; and T3N1M0, T1N2M0, T2N2M0, T3N2M0, stage IIIA. The
TNM subsets in stage IIIB-T4 any N M0, any T N3M0, and in stage IV-any T any N M1,
remain the same. Analysis of a collected database representing all clinical, surgical-pathologic,
and follow-up information for 5,319 patients treated for primary lung cancer confirmed
the validity of the TNM and stage grouping classification schema.