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      Function and regulation of CREB family transcription factors in the nervous system.

      1 ,
      Neuron
      Elsevier BV

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          Abstract

          CREB and its close relatives are now widely accepted as prototypical stimulus-inducible transcription factors. In many cell types, these factors function as effector molecules that bring about cellular changes in response to discrete sets of instructions. In neurons, a wide range of extracellular stimuli are capable of activating CREB family members, and CREB-dependent gene expression has been implicated in complex and diverse processes ranging from development to plasticity to disease. In this review, we focus on the current level of understanding of where, when, and how CREB family members function in the nervous system.

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          Author and article information

          Journal
          Neuron
          Neuron
          Elsevier BV
          0896-6273
          0896-6273
          Aug 15 2002
          : 35
          : 4
          Affiliations
          [1 ] Department of Neuroscience, Howard Hughes Medical Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21205, USA.
          Article
          S0896627302008280
          10.1016/s0896-6273(02)00828-0
          12194863
          d75a3443-9e9c-4299-a9c2-feda8aa3f3a8
          History

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