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      Constituents of stem bark of Callistemon rigidus showing inhibitory effects on mouse alpha-amylase activity.

      Biological & pharmaceutical bulletin
      Administration, Oral, Animals, Benzofurans, isolation & purification, pharmacology, Blood Glucose, analysis, Enzyme Inhibitors, Gastrointestinal Tract, enzymology, Hypoglycemic Agents, Male, Mice, Mice, Inbred Strains, Molecular Structure, Myrtaceae, chemistry, Plant Bark, Plant Extracts, Plant Stems, Stilbenes, alpha-Amylases, antagonists & inhibitors, blood

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          Abstract

          From stem bark of Callistemon rigidus (Myrtaceae), piceatannol and scirpusin B were isolated as components that exhibit inhibitory effects on alpha-amylase activity in isolated mouse plasma. In particular, scirpusin B also inhibited alpha-amylase in mouse gastrointestinal tract. Thus, we expect the depressive effect on the elevation of postprandial blood glucose may be a new medicinal use of this compound as well as the plant itself.

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