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      Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method.

      Clinica chimica acta; international journal of clinical chemistry
      Elsevier BV

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          Abstract

          A new colorimetric method for quantitative analysis of serum lipid peroxide, free of interference from sialic acids, has been developed. We have used the thiobarbituric acid dissolved in sodium sulfate solution and both liberation of lipid peroxide and color reaction have been performed simultaneously by heating serum protein precipitate with this reagent in a weak acid solution. The new method is specific and facilitates the precise measurements of serum lipid peroxide. The average values determined by the new method increased slightly with age in healthy subjects. In patients with sequelae of cerebrovascular disorders, serum lipid peroxide values were higher than in healthy controls. These results may demonstrate the important role of lipid peroxide in aging and cerebrovascular disorders.

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          Author and article information

          Journal
          Clin Chim Acta
          Clinica chimica acta; international journal of clinical chemistry
          Elsevier BV
          0009-8981
          0009-8981
          Nov 15 1978
          : 90
          : 1
          Article
          0009-8981(78)90081-5
          10.1016/0009-8981(78)90081-5
          719890
          d76d276c-154b-4e6c-96f6-69c4b3340360
          History

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