For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
19
views
5
references
 Top references
cited by
68
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
1 collections
    0
    shares
      64
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: not found

      Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Vertical Transmission in Neonates Born to Mothers With Coronavirus Disease 2019 (COVID-19) Pneumonia

      other
      Author(s): , MD, , MD, PhD, , MD, PhD, , MD, PhD, , MD, , MD, PhD, , MD, PhD, , MD, PhD , , MD, PhD
      Publication date (Electronic):
      Journal: Obstetrics and Gynecology
      Publisher: Lippincott Williams & Wilkins

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          One of seven neonates born to women with symptomatic coronavirus 2019 (COVID-19) infection tested positive for the infection and was asymptomatic.

          Related collections

          Most cited references5

          • Record: found
          • Abstract: found
          • Article: not found

          Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records

          Huijun Chen, Juanjuan Guo, Chen Wang … (2020)
          Summary Background Previous studies on the pneumonia outbreak caused by the 2019 novel coronavirus disease (COVID-19) were based on information from the general population. Limited data are available for pregnant women with COVID-19 pneumonia. This study aimed to evaluate the clinical characteristics of COVID-19 in pregnancy and the intrauterine vertical transmission potential of COVID-19 infection. Methods Clinical records, laboratory results, and chest CT scans were retrospectively reviewed for nine pregnant women with laboratory-confirmed COVID-19 pneumonia (ie, with maternal throat swab samples that were positive for severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) who were admitted to Zhongnan Hospital of Wuhan University, Wuhan, China, from Jan 20 to Jan 31, 2020. Evidence of intrauterine vertical transmission was assessed by testing for the presence of SARS-CoV-2 in amniotic fluid, cord blood, and neonatal throat swab samples. Breastmilk samples were also collected and tested from patients after the first lactation. Findings All nine patients had a caesarean section in their third trimester. Seven patients presented with a fever. Other symptoms, including cough (in four of nine patients), myalgia (in three), sore throat (in two), and malaise (in two), were also observed. Fetal distress was monitored in two cases. Five of nine patients had lymphopenia (<1·0 × 10⁹ cells per L). Three patients had increased aminotransferase concentrations. None of the patients developed severe COVID-19 pneumonia or died, as of Feb 4, 2020. Nine livebirths were recorded. No neonatal asphyxia was observed in newborn babies. All nine livebirths had a 1-min Apgar score of 8–9 and a 5-min Apgar score of 9–10. Amniotic fluid, cord blood, neonatal throat swab, and breastmilk samples from six patients were tested for SARS-CoV-2, and all samples tested negative for the virus. Interpretation The clinical characteristics of COVID-19 pneumonia in pregnant women were similar to those reported for non-pregnant adult patients who developed COVID-19 pneumonia. Findings from this small group of cases suggest that there is currently no evidence for intrauterine infection caused by vertical transmission in women who develop COVID-19 pneumonia in late pregnancy. Funding Hubei Science and Technology Plan, Wuhan University Medical Development Plan.
          Article 0 comments Cited 1639 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia

            Huaping Zhu, Lin Wang, Chengzhi Fang … (2020)
            The newly identified 2019-nCoV, which appears to have originated in Wuhan, the capital city of Hubei province in central China, is spreading rapidly nationwide. A number of cases of neonates born to mothers with 2019-nCoV pneumonia have been recorded. However, the clinical features of these cases have not been reported, and there is no sufficient evidence for the proper prevention and control of 2019-nCoV infections in neonates.
            Article 0 comments Cited 577 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition)

              Laishuan Wang, Yuan Shi, Tiantian Xiao … (2020)
              Since December 2019, there has been an outbreak of novel coronavirus (2019-nCoV) infection in China. Two cases of neonates with positive 2019-nCoV tests have been reported. Due to the immature immune system and the possibility of vertical transmission from mother to infant, neonates have become a high-risk group susceptible to 2019-nCoV, which emphasize a close cooperation from both perinatal and neonatal pediatrics. In neonatal intensive care unit (NICU), to prevent and control infection, there should be practical measures to ensure the optimal management of children potentially to be infected. According to the latest 2019-nCoV national management plan and the actual situation, the Chinese Neonatal 2019-nCoV expert working Group has put forward measures on the prevention and control of neonatal 2019-nCoV infection.
              Article 0 comments Cited 144 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Obstet Gynecol
                Journal ID (iso-abbrev): Obstet Gynecol
                Journal ID (publisher-id): ong
                Title: Obstetrics and Gynecology
                Publisher: Lippincott Williams & Wilkins
                ISSN (Print): 0029-7844
                ISSN (Electronic): 1873-233X
                Publication date (Electronic): 24 April 2020
                Electronic Location Identifier: 10.1097/AOG.0000000000003926
                Affiliations
                Departments of Pediatrics, Obstetrics and Gynecology, and Clinical Laboratory, Tongji Hospital, and the Department of Biochemistry and Molecular Biology, Basic Medicine School, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China; and the Divisions of Obstetrics and Gynecology and Pediatrics and Neonatal Critical Care, “A. Béclère” Medical Centre, Paris Saclay University Hospitals APHP and Paris Saclay University, Paris, France.
                Author notes
                Corresponding author: Daniele De Luca, MD, PhD, Service de Pédiatrie et Réanimation Néonatale, GHU Paris Sud, Hôpital “A. Béclère,” Clamart, France; email: dm.deluca@ 123456icloud.com .
                Article
                Publisher ID: ONG-20-548
                DOI: 10.1097/AOG.0000000000003926
                PMC ID: 7219851
                PubMed ID: 32332320
                SO-VID: d7cace95-88e5-4cf7-b206-0cced104ecea
                Copyright © © 2020 by the American College of Obstetricians and Gynecologists. Published by Wolters Kluwer Health, Inc. All rights reserved.
                License:

                This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.

                History
                Date received : 10 March 2020
                Date revision received : 15 April 2020
                Date accepted : 17 April 2020
                Categories
                Subject: Research Letter

                Data availability:

                Comments

                Comment on this article

                scite_

                Similar content64

                See all similar

                Cited by66

                See all cited by

                Most referenced authors133

                See all reference authors