Andreas Drolz 1 , Thomas Horvatits 1 , Barbara Michl 1 , Kevin Roedl 1 , Peter Schellongowski 2 , Ulrike Holzinger 1 , Christian Zauner 1 , Gottfried Heinz 3 , Christian Madl 4 , Michael Trauner 1 , Valentin Fuhrmann 5
Hypoxic hepatitis (HH) is a frequent and life-threatening complication associated with states of oxygen depletion in critically ill patients. Ischemia and reperfusion contribute to liver injury in HH. Experimental data suggest beneficial effects of statins in hepatic ischemia/reperfusion injury. This study was conducted to investigate whether statin treatment prior to intensive care unit (ICU) admission affects incidence rates and severity of HH.