DNA cages with icosahedral symmetry in bionanotechnology

Abstract

Blueprints of polyhedral cages with icosahedral symmetry made of circular DNA molecules are provided. The basic rule is that every edge of the cage is met twice in opposite directions by the DNA strand, and vertex junctions are realised by a set of admissible junction types. As nanocontainers for cargo storage and delivery, the icosidodecahedral cages are of special interest as they have the largest volume per surface ratio of all cages discussed here.