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      Antibacterial coatings on titanium implants.

      Journal of Biomedical Materials Research. Part B, Applied Biomaterials
      Anti-Bacterial Agents, chemistry, pharmacology, therapeutic use, Bacterial Adhesion, drug effects, Biofilms, Coated Materials, Biocompatible, Drug Carriers, Humans, Materials Testing, Nitric Oxide, Polymers, Prostheses and Implants, Prosthesis-Related Infections, prevention & control, Surface Properties, Titanium

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          Abstract

          Titanium and titanium alloys are key biomedical materials because of their good biocompatibility and mechanical properties. Nevertheless, infection on and around titanium implants still remains a problem which is usually difficult to treat and may lead to eventual implant removal. As a result, preventive measures are necessary to mitigate implant-frelated infection. One important strategy is to render the implant surface antibacterial by impeding the formation of a biofilm. A number of approaches have been proposed for this purpose and they are reviewed in this article. (c) 2009 Wiley Periodicals, Inc.

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