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      Pain catastrophizing and associated factors in preoperative total knee arthroplasty in Lanzhou, China: a cross-sectional study

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          Abstract

          Background

          Pain catastrophizing in preoperative total knee arthroplasty (TKA) patients is associated with several poorly characterised factors in the literature. This study investigated the current state and associated factors of preoperative pain catastrophizing in patients undergoing TKA.

          Methods

          This descriptive cross-sectional study was conducted at the orthopedics ward of two tertiary hospitals in Lanzhou, China. Pain catastrophizing was measured using the Chinese versions of the Pain Catastrophizing Scale, Short Form-36 (physical function domain), Numerical Rating Scale, Oxford Knee Score, Hospital Anxiety and Depression Scale, and Life Orientation Test-Revised.

          Results

          The study included 360 participants. Preoperative TKA pain catastrophizing in all patients was high, with a mean score of 24.92 (SD: 12.38). The stepwise multiple linear regression analysis revealed anxiety ( β = 0.548, P < 0.01), education level ( β =  − 0.179, P < 0.01), physical function ( β =  − 0.156, P < 0.01), and pain intensity during activity ( β = 0.105, P = 0.015) as associated factors for pain catastrophizing, possibly explaining 51.2% of the total variation ( F = 95.149, P < 0.01).

          Conclusion

          Anxiety was the most relevant factor for pain catastrophizing in patients with preoperative TKA. Lower education levels, poor physical function, and stronger pain intensity during the activity were also associated with pain catastrophizing.

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          Most cited references42

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          The hospital anxiety and depression scale.

          A self-assessment scale has been developed and found to be a reliable instrument for detecting states of depression and anxiety in the setting of an hospital medical outpatient clinic. The anxiety and depressive subscales are also valid measures of severity of the emotional disorder. It is suggested that the introduction of the scales into general hospital practice would facilitate the large task of detection and management of emotional disorder in patients under investigation and treatment in medical and surgical departments.
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            Pain catastrophizing: a critical review.

            Pain catastrophizing is conceptualized as a negative cognitive-affective response to anticipated or actual pain and has been associated with a number of important pain-related outcomes. In the present review, we first focus our efforts on the conceptualization of pain catastrophizing, highlighting its conceptual history and potential problem areas. We then focus our discussion on a number of theoretical mechanisms of action: appraisal theory, attention bias/information processing, communal coping, CNS pain processing mechanisms, psychophysiological pathways and neural pathways. We then offer evidence to suggest that pain catastrophizing represents an important process factor in pain treatment. We conclude by offering what we believe represents an integrated heuristic model for use by researchers over the next 5 years; a model we believe will advance the field most expediently.
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              Poorly controlled postoperative pain: prevalence, consequences, and prevention

              Tong Gan (2017)
              This review provides an overview of the clinical issue of poorly controlled postoperative pain and therapeutic approaches that may help to address this common unresolved health-care challenge. Postoperative pain is not adequately managed in greater than 80% of patients in the US, although rates vary depending on such factors as type of surgery performed, analgesic/anesthetic intervention used, and time elapsed after surgery. Poorly controlled acute postoperative pain is associated with increased morbidity, functional and quality-of-life impairment, delayed recovery time, prolonged duration of opioid use, and higher health-care costs. In addition, the presence and intensity of acute pain during or after surgery is predictive of the development of chronic pain. More effective analgesic/anesthetic measures in the perioperative period are needed to prevent the progression to persistent pain. Although clinical findings are inconsistent, some studies of local anesthetics and nonopioid analgesics have suggested potential benefits as preventive interventions. Conventional opioids remain the standard of care for the management of acute postoperative pain; however, the risk of opioid-related adverse events can limit optimal dosing for analgesia, leading to poorly controlled acute postoperative pain. Several new opioids have been developed that modulate μ-receptor activity by selectively engaging intracellular pathways associated with analgesia and not those associated with adverse events, creating a wider therapeutic window than unselective conventional opioids. In clinical studies, oliceridine (TRV130), a novel μ-receptor G-protein pathway-selective modulator, produced rapid postoperative analgesia with reduced prevalence of adverse events versus morphine.
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                Author and article information

                Contributors
                18093188800@163.com
                douxm@lzu.edu.cn
                Journal
                BMC Musculoskelet Disord
                BMC Musculoskelet Disord
                BMC Musculoskeletal Disorders
                BioMed Central (London )
                1471-2474
                28 May 2022
                28 May 2022
                2022
                : 23
                Affiliations
                [1 ]GRID grid.412643.6, ISNI 0000 0004 1757 2902, The First Clinical Medical College, Lanzhou University, ; Lanzhou, Gansu China
                [2 ]GRID grid.411294.b, ISNI 0000 0004 1798 9345, Oncology Surgery Department, , Lanzhou University Second Hospital, ; Lanzhou, China
                [3 ]GRID grid.417234.7, ISNI 0000 0004 1808 3203, Department of Spine Minimally Invasive Orthopedics, , Gansu Provincial Hospital of Traditional Chinese Medicine, ; Lanzhou, Gansu China
                [4 ]GRID grid.417234.7, ISNI 0000 0004 1808 3203, Department of Anesthesia and Surgery, , Gansu Provincial Hospital of Traditional Chinese Medicine, ; Lanzhou, Gansu China
                [5 ]GRID grid.417234.7, ISNI 0000 0004 1808 3203, Department of Emergency, , Gansu Provincial Hospital of Traditional Chinese Medicine, ; Lanzhou, Gansu China
                [6 ]GRID grid.418117.a, ISNI 0000 0004 1797 6990, Clinical college of Traditional Chinese Medicine, , Gansu university of Chinese medicine, ; No. 418, guazhou Road, Qilihe District, Lanzhou, 730000 Gansu Province China
                [7 ]GRID grid.418117.a, ISNI 0000 0004 1797 6990, The First Affiliated Hospital, , Gansu University of Traditional Chinese Medicine, ; Lanzhou, Gansu, China
                [8 ]GRID grid.411294.b, ISNI 0000 0004 1798 9345, Department of Nursing, , Lanzhou University Second Hospital, ; Lanzhou, China
                Article
                5435
                10.1186/s12891-022-05435-1
                9145464
                d88fbde8-888a-4646-90b7-27850c2cbd46
                © The Author(s) 2022

                Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                Funding
                Funded by: the National Natural Science Foundation of China
                Award ID: 81760877
                Funded by: Gansu Province Science and Technology Planning Project (Major Project)21ZD4FA009
                Categories
                Research
                Custom metadata
                © The Author(s) 2022

                Orthopedics
                pain catastrophizing,anxiety,pain,associated factors,total knee arthroplasty
                Orthopedics
                pain catastrophizing, anxiety, pain, associated factors, total knee arthroplasty

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