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      C-H bond functionalization: emerging synthetic tools for natural products and pharmaceuticals.

      Angewandte Chemie (International Ed. in English)

      Stereoisomerism, chemistry, chemical synthesis, Pharmaceutical Preparations, analogs & derivatives, Methane, Metals, Imines, Hydrogen, Catalysis, Carbon, Biological Products, Alkylation

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          Abstract

          The direct functionalization of C-H bonds in organic compounds has recently emerged as a powerful and ideal method for the formation of carbon-carbon and carbon-heteroatom bonds. This Review provides an overview of C-H bond functionalization strategies for the rapid synthesis of biologically active compounds such as natural products and pharmaceutical targets. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

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          Journal
          22887739
          10.1002/anie.201201666

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