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      Multiple behavioural impulsivity tasks predict prospective alcohol involvement in adolescents

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          Abstract

          Aims

          We investigated reciprocal prospective relationships between multiple behavioural impulsivity tasks (assessing delay discounting, risk-taking and disinhibition) and alcohol involvement (consumption, drunkenness and problems) among adolescents. We hypothesized that performance on the tasks would predict subsequent alcohol involvement, and that alcohol involvement would lead to increases in behavioural impulsivity over time.

          Design

          Cross-lagged prospective design in which impulsivity and alcohol involvement were assessed five times over 2 years (once every 6 months, on average).

          Setting

          Classrooms in secondary schools in North West England.

          Participants

          Two hundred and eighty-seven adolescents (51.2% male) who were aged 12 or 13 years at study enrolment.

          Measurements

          Participants reported their alcohol involvement and completed computerized tasks of disinhibition, delay discounting and risk-taking at each assessment. Cross-sectional and prospective relationships between the variables of interest were investigated using cross-lagged analyses.

          Findings

          All behavioural impulsivity tasks predicted a composite index of alcohol involvement 6 months later (all Ps < 0.01), and these prospective relationships were reliable across the majority of time-points. Importantly, we did not observe the converse relationship across time: alcohol involvement did not predict performance on behavioural impulsivity tasks at any subsequent time point.

          Conclusions

          Several measures of impulsivity predict escalation in alcohol involvement in young adolescents, but alcohol use does not appear to alter impulsivity.

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          Most cited references50

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          How to Use a Monte Carlo Study to Decide on Sample Size and Determine Power

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            Impulsivity as a vulnerability marker for substance-use disorders: review of findings from high-risk research, problem gamblers and genetic association studies.

            There is a longstanding association between substance-use disorders (SUDs) and the psychological construct of impulsivity. In the first section of this review, personality and neurocognitive data pertaining to impulsivity will be summarised in regular users of four classes of substance: stimulants, opiates, alcohol and 3,4-methylenedioxymethamphetamine (MDMA). Impulsivity in these groups may arise via two alternative mechanisms, which are not mutually exclusive. By one account, impulsivity may occur as a consequence of chronic exposure to substances causing harmful effects on the brain. By the alternative account, impulsivity pre-dates SUDs and is associated with the vulnerability to addiction. We will review the evidence that impulsivity is associated with addiction vulnerability by considering three lines of evidence: (i) studies of groups at high-risk for development of SUDs; (ii) studies of pathological gamblers, where the harmful consequences of the addiction on brain structure are minimised, and (iii) genetic association studies linking impulsivity to genetic risk factors for addiction. Within each of these three lines of enquiry, there is accumulating evidence that impulsivity is a pre-existing vulnerability marker for SUDs.
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              Impulsivity as a determinant and consequence of drug use: a review of underlying processes.

              Impulsive behaviors are closely linked to drug use and abuse, both as contributors to use and as consequences of use. Trait impulsivity is an important determinant of drug use during development, and in adults momentary 'state' increases in impulsive behavior may increase the likelihood of drug use, especially in individuals attempting to abstain. Conversely, acute and chronic effects of drug use may increase impulsive behaviors, which may in turn facilitate further drug use. However, these effects depend on the behavioral measure used to assess impulsivity. This article reviews data from controlled studies investigating different measures of impulsive behaviors, including delay discounting, behavioral inhibition and a newly proposed measure of inattention. Our findings support the hypothesis that drugs of abuse alter performance across independent behavioral measures of impulsivity. The findings lay the groundwork for studying the cognitive and neurobiological substrates of impulsivity, and for future studies on the role of impulsive behavior as both facilitator and a result of drug use.
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                Author and article information

                Journal
                Addiction
                Addiction
                add
                Addiction (Abingdon, England)
                BlackWell Publishing Ltd (Oxford, UK )
                0965-2140
                1360-0443
                November 2013
                14 August 2013
                : 108
                : 11
                : 1916-1923
                Affiliations
                [1 ]Department of Psychological Sciences, University of Liverpool Liverpool, UK
                [2 ]School of Psychology, University of Utrecht Utrecht, the Netherlands
                [3 ]Centre for Public Health, Liverpool John Moores University Liverpool, UK
                [* ]Division of Applied Medicine (Psychiatry), School of Medicine and Dentistry, University of Aberdeen UK
                []Centre for Youth Substance Abuse Research, The University of Queensland Australia
                Author notes
                Correspondence to: Matt Field, Department of Psychological Sciences, University of Liverpool, Liverpool L69 7ZA, UK. E-mail: mfield@ 123456liv.ac.uk
                Article
                10.1111/add.12283
                4230409
                23795646
                d92b904a-57c9-40b3-bfb5-5813ddfeac20
                © 2013 The Authors. Addiction published by John Wiley & Sons Ltd on behalf of the Society for the Study of Addiction.

                This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 21 December 2012
                : 22 February 2013
                : 20 June 2013
                Categories
                Research Reports

                Clinical Psychology & Psychiatry
                adolescents,alcohol,delay discounting,disinhibition,impulsivity,risk-taking

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