Beitrag zur Ultrastruktur phagozytierender Granulozyten bei progressiver septischer Granulomatose des Kindes

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Abstract

Electron-microscopic studies on granulocytes of a boy with chronic granulomatous disease are demonstrated in comparison with those of a healthy person. During the process of phagocytosis of staphylococcus aureus the granulocytes of the patient show morphologic changes that are different from normal. There were no hints to a dysfunction of fusion of the granules with the phagocytic vacuole. Deficient degranulation may be explained by a defect of the positive granule-taxis to the phagocytic vacuole.

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Author and article information

Journal

Journal ID (publisher-id): PAT

Journal ID (nlm-ta): Pathobiology

Journal ID (doi): 10.1159/issn.1015-2008

Title: Pathobiology

Publisher: S. Karger AG

ISSN (Print): 1015-2008

ISSN (Electronic): 1423-0291

Publication date Subscription-year: 1972

Publication date (Print): 1972

Publication date (Electronic): 03 October 2008

Volume: 38

Issue: 2

Pages: 133-143

Affiliations

Kinderklinik, Pathologisches Institut und Institut für Medizinische Mikrobiologie und Epidemiologie der Medizinischen Akademie «Carl Gustav Carus», Dresden

Article

Publisher ID: 162398 Other ID: Pathol Microbiol (Basel) 1972;38:133–143

DOI: 10.1159/000162398

SO-VID: d955115e-3b2c-4e1c-9e7c-899cabfb1e7c

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

History

Date received : 01 September 1971

Date accepted : 06 October 1971

Page count

Pages: 11

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