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      Neuroscience, Molecular Biology, and the Childhood Roots of Health Disparities : Building a New Framework for Health Promotion and Disease Prevention

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      JAMA

      American Medical Association (AMA)

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          Abstract

          A scientific consensus is emerging that the origins of adult disease are often found among developmental and biological disruptions occurring during the early years of life. These early experiences can affect adult health in 2 ways--either by cumulative damage over time or by the biological embedding of adversities during sensitive developmental periods. In both cases, there can be a lag of many years, even decades, before early adverse experiences are expressed in the form of disease. From both basic research and policy perspectives, confronting the origins of disparities in physical and mental health early in life may produce greater effects than attempting to modify health-related behaviors or improve access to health care in adulthood.

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          Author and article information

          Journal
          JAMA
          JAMA
          American Medical Association (AMA)
          0098-7484
          June 03 2009
          June 03 2009
          : 301
          : 21
          : 2252
          Article
          10.1001/jama.2009.754
          19491187
          © 2009

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