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      Effect of balloon inflation‐induced acute ischemia on QT dispersion during percutaneous transluminal coronary angioplasty

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          Abstract

          Background: QT dispersion (QTd = QT max ‐ QT min) measured as interlead variability of QT interval reflects the spatial inhomogeneity of ventricular repolarization times, and increased QTd may provide a substrate for malignant ventricular arrhythmias. Ischemia is associated with regional abnormalities of conduction and repolarization.

          Hypothesis: This study aimed to investigate the effect of acute ischemia on QTd during successful percutaneous transluminal coronary angioplasty (PTCA).

          Methods: Forty‐three patients (10 women, 33 men, mean age 56 years) were enrolled in the study. Electrocardiogram (ECG) recordings were taken before PTCA and during balloon inflation period. QT maximum (QT max), QT minimum (QT min), and QTd (QT max ‐ QT min) values were calculated from the surface ECG.

          Results: There was no difference among QT max values (p = 0.6). Mean QT min during balloon inflation was lower than before PTCA (368 ± 45 vs. 380 ± 41 ms, p = 0.002). The difference between QTd values before and during balloon inflation was statistically important (65 ± 9 vs. 76 ± 10 ms, p = 0.001). This difference is caused by a decrease in QT min during balloon inflation.

          Conclusion: Acute reversible myocardial ischemia induced by balloon inflation causes an increase in QTd value, and this increment is the result of a decrease in QT min interval. Therefore, QTd may be a marker of reversible myocardial ischemia.

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          Author and article information

          Journal
          Clin Cardiol
          Clin Cardiol
          10.1002/(ISSN)1932-8737
          CLC
          Clinical Cardiology
          Wiley Periodicals, Inc. (New York )
          0160-9289
          1932-8737
          03 February 2009
          January 1999
          : 22
          : 1 ( doiID: 10.1002/clc.v22:1 )
          : 21-24
          Affiliations
          [ 1 ]Hacettepe University, Faculty of Medicine, Department of Cardiology, Ankara, Turkey
          Author notes
          [* ]61 Sheldrick Close SW19 2UQ London UK
          Article
          PMC6655594 PMC6655594 6655594 CLC4960220109
          10.1002/clc.4960220109
          6655594
          9929750
          Copyright © 1999 Wiley Periodicals, Inc.
          Page count
          Figures: 2, Tables: 1, References: 35, Pages: 4
          Categories
          Clinical Investigation
          Clinical Investigations
          Custom metadata
          2.0
          January 1999
          Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.2.1 mode:remove_FC converted:09.05.2019

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