Endomyocardial fibrosis and calcification in an elderly patient

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Abstract

Endomyocardial fibrosis (EMF) is a rare restrictive cardiomyopathy in developed countries. The prognosis of EMF depends on severity of heart failure, and it is generally poor as there is no proven specific effective therapy. We have experienced a rare case of EMF in an elderly Japanese man.

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Most cited references 2

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A population study of endomyocardial fibrosis in a rural area of Mozambique.

Fernanda M. Ferreira, D Sidi, Ana Olga Mocumbi … (2008)

Endomyocardial fibrosis is the most common restrictive cardiomyopathy worldwide. It has no specific treatment and carries a poor prognosis, since most patients present with advanced heart failure. On the basis of clinical series, regional variations in distribution have been reported within several countries in Africa, Asia, and South America, but large-scale data are lacking on the epidemiologic features and early stages of the disease. We used transthoracic echocardiography to determine the prevalence of endomyocardial fibrosis in a rural area of Mozambique. We screened a random sample of 1063 subjects of all age groups selected by clustering. Major and minor diagnostic criteria were defined, and a severity score was developed and applied. Cases were classified according to the distribution and severity of the lesions in the heart. The estimated overall prevalence of endomyocardial fibrosis was 19.8%, or 211 of 1063 subjects (95% confidence interval [CI], 17.4 to 22.2). The prevalence was highest among persons 10 to 19 years of age (28.1%, or 73 of 260 subjects [95% CI, 22.6 to 33.6]) and was higher among male than among female subjects (23.0% vs. 17.5%, P=0.03). The most common form was biventricular endomyocardial fibrosis (a prevalence of 55.5%, or 117 of 211 subjects [95% CI, 48.8 to 62.2]), followed by right-sided endomyocardial fibrosis (a prevalence of 28.0%, or 59 of 211 subjects [95% CI, 21.9 to 34.1]). Most affected subjects had mild-to-moderate structural and functional echocardiographic abnormalities. Only 48 persons with endomyocardial fibrosis (22.7%) were symptomatic. The frequency of familial occurrence was high. Endomyocardial fibrosis is common in a rural area of Mozambique. By using echocardiography, we were able to detect early, asymptomatic stages of the disease. These findings may aid in the study of the pathogenesis of the disease and in the development of new management strategies. 2008 Massachusetts Medical Society

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Endomyocardial Fibrosis: A Rare Case of Diastolic Heart Failure in a European Caucasian Elderly Woman.

Luca Conte, Majlinda Fejzo, Andrea Rossi … (2018)

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Author and article information

Contributors

Tomohiro Nakamura:

ORCID: https://orcid.org/0000-0003-0051-2033

nakamuratomopon@gmail.com

Journal

Journal ID (nlm-ta): J Gen Fam Med

Journal ID (iso-abbrev): J Gen Fam Med

Journal ID (doi): 10.1002/(ISSN)2189-7948

Journal ID (publisher-id): JGF2

Title: Journal of General and Family Medicine

Publisher: John Wiley and Sons Inc. (Hoboken )

ISSN (Print): 2189-6577

ISSN (Electronic): 2189-7948

Publication date (Electronic): 03 April 2019

Publication date Collection: July 2019

Volume: 20

Issue: 4 ( doiID: 10.1002/jgf2.2019.20.issue-4 )

Pages: 157-158

Affiliations

[ ¹ ] Department of Internal Medicine Saitama Citizens Medical Center Saitama Japan

Author notes

[*] [* ] Correspondence

Tomohiro Nakamura, Saitama Citizens Medical Center, Saitama, Japan.

Email: nakamuratomopon@ 123456gmail.com

Author information

Tomohiro Nakamura https://orcid.org/0000-0003-0051-2033

Article

Publisher ID: JGF2246

DOI: 10.1002/jgf2.246

PMC ID: 6612774

SO-VID: d981d701-d4c5-44e6-bbd5-0f1a59d382b5

License:

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

History

Date received : 20 February 2019

Date revision received : 09 March 2019

Date accepted : 17 March 2018

Page count

Figures: 2, Tables: 0, Pages: 2, Words: 649

Custom metadata

source-schema-version-number 2.0

component-id jgf2246

cover-date July 2019

details-of-publishers-convertor Converter:WILEY_ML3GV2_TO_NLMPMC version:5.6.5 mode:remove_FC converted:08.07.2019

Keywords: cardiac biopsy,cardiovascular medicine,elderly,endomyocardial fibrosis

Data availability:

Keywords: cardiac biopsy, cardiovascular medicine, elderly, endomyocardial fibrosis

Endomyocardial fibrosis and calcification in an elderly patient

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