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      Ultrastructure of the Outer Nuclear Layer of the Rabbit Retina following Coagulation with the Ruby Laser


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          The electron microscopical findings in the outer nuclear layer of the rabbit retina following exposure of ruby laser beams are described: half-an-hour following laser coagulation the nuclei show a conglomeration of the chromatin. 20 h after coagulation, fragments of outer and inner segments of the rods are observed in the outer nuclear layer. Some cells also contain homogeneous and dense nuclear aggregations of small electrondense granules. 25 h after laser application, the alterations in the nuclei are more pronounced : the chromatin shows a marginal condensation or has sickle-shaped appearance. 35 h after coagulation, Müller cells appear in the outer nuclear layer. 10 h later these cells accumulate, whereas the outer nuclear cells decrease. Between 45 and 116 h, macrophages and Müller cells are observed in the outer nuclear layer.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          03 December 2009
          : 8
          : 1
          : 34-42
          University Eye Hospital (Head: Prof. H. Sautter) Hamburg
          264797 Ophthalmic Res 1976;8:34–42
          © 1976 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          : 02 September 1974
          : 03 February 1975
          Page count
          Pages: 9

          Vision sciences,Ophthalmology & Optometry,Pathology
          Ultrastructure of retina,Retina,Pigment epithelium,Laser coagulation,Outer nuclear layer,Photoreceptors,Rabbit,Ruby laser


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