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      First successful treatment of Nocardia farcinica brain abscess with moxifloxacin.

      The Journal of Infection
      Anti-Infective Agents, therapeutic use, Aza Compounds, Biopsy, Needle, Brain Abscess, drug therapy, Fluoroquinolones, Humans, Immunocompromised Host, Immunosuppressive Agents, administration & dosage, Kidney Transplantation, immunology, Lung Abscess, pathology, Male, Microbial Sensitivity Tests, Middle Aged, Nocardia, isolation & purification, Nocardia Infections, Quinolines, RNA, Ribosomal, 16S, genetics, Tomography, X-Ray Computed, Treatment Outcome

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          Abstract

          Nocardia farcinica is an emerging pathogen in immunosuppressed patients causing both localized and disseminated infections. Many strains of this species are multidrug-resistant and require long-term antibiotic therapy, and consequently the choice of an oral treatment can be problematic. We report here the first case of successful treatment of N. farcinica brain abscess in a renal transplant recipient with an extended-spectrum fluoroquinolone, moxifloxacin.

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