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Synthesis and Study of Analgesic and Anti-inflammatory Activities of Amide Derivatives of Ibuprofen.

Author(s): Abbas Ahmadi, Mohsen Khalili, Zahra Olama, Shirin Karami, Babak Nahri-Niknafs

Publication date: 2017

Journal: Mini Reviews in Medicinal Chemistry

Publisher: Bentham Science Publishers

Keywords: NSAIDs, Analgesic, ibuprofen, pharmacological heterocyclic amides, anti-inflammatory

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Abstract

Nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most widely used drugs worldwide and represent a mainstay in the therapy of acute and chronic pain and inflammation. The traditional NSAIDs like ibuprofen (I) contain free carboxylic acid group which can produce gastrointestinal (GI) damage for long-term use.

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PubMed ID:: 28029080

DOI:: 10.2174/1389557516666161226155951

Keywords: NSAIDs,Analgesic,ibuprofen,pharmacological heterocyclic amides,anti-inflammatory

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Keywords: NSAIDs, Analgesic, ibuprofen, pharmacological heterocyclic amides, anti-inflammatory

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