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      Estimation of the Concentration of Low-Density Lipoprotein Cholesterol in Plasma, Without Use of the Preparative Ultracentrifuge

      1 , 1 , 1

      Clinical Chemistry

      Oxford University Press (OUP)

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          Abstract

          A method for estimating the cholesterol content of the serum low-density lipoprotein fraction (Sf0-20) is presented. The method involves measurements of fasting plasma total cholesterol, triglyceride, and high-density lipoprotein cholesterol concentrations, none of which requires the use of the preparative ultracentrifuge. Comparison of this suggested procedure with the more direct procedure, in which the ultracentrifuge is used, yielded correlation coefficients of .94 to .99, depending on the patient population compared.

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          Author and article information

          Journal
          Clinical Chemistry
          Oxford University Press (OUP)
          0009-9147
          1530-8561
          June 01 1972
          June 01 1972
          January 21 2020
          June 01 1972
          June 01 1972
          January 21 2020
          : 18
          : 6
          : 499-502
          Affiliations
          [1 ]Biometrics Research Branch (W.T.F.) and the Molecular Disease Branch (R.I.L. and D.S.F.), National Heart and Lung Institute, 9000 Rockville Pike, Bethesda, Md. 20014
          Article
          10.1093/clinchem/18.6.499
          4337382
          © 2020

          https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model

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