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      A multicenter study to quantify systematic variations and associated uncertainties in source positioning with commonly used HDR afterloaders and ring applicators for the treatment of cervical carcinomas.

      1 , 2 , 3
      Medical physics
      Wiley

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          Abstract

          The reconstruction of radiation source position in the treatment planning system is a key part of the applicator reconstruction process in high dose rate (HDR) brachytherapy treatment of cervical carcinomas. The steep dose gradients, of as much as 12%/mm, associated with typical cervix treatments emphasize the importance of accurate and precise determination of source positions. However, a variety of methodologies with a range in associated measurement uncertainties, of up to ±2.5 mm, are currently employed by various centers to do this. In addition, a recent pilot study by Awunor et al. ["Direct reconstruction and associated uncertainties of (192)Ir source dwell positions in ring applicators using gafchromic film in the treatment planning of HDR brachytherapy cervix patients," Phys. Med. Biol. 58, 3207-3225 (2013)] reported source positional differences of up to 2.6 mm between ring sets of the same type and geometry. This suggests a need for a comprehensive study to assess and quantify systematic source position variations between commonly used ring applicators and HDR afterloaders across multiple centers.

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          Author and article information

          Journal
          Med Phys
          Medical physics
          Wiley
          2473-4209
          0094-2405
          Aug 2015
          : 42
          : 8
          Affiliations
          [1 ] The Medical Physics Department, The James Cook University Hospital, Marton Road, Middlesbrough TS4 3BW, England, United Kingdom.
          [2 ] Department of Radiotherapy, General Hospital of Vienna, Vienna A-1090, Austria.
          [3 ] Department of Radiotherapy, Comprehensive Cancer Center, Medical University of Vienna, Vienna A-1090, Austria.
          Article
          10.1118/1.4923173
          26233177
          da1cd2a2-1c54-40d0-a398-cb47482e2b2f
          History

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