3
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Mortality of atomic bomb survivors predicted from laboratory animals.

      Read this article at

      ScienceOpenPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Exposure, pathology and mortality data for mice, dogs and humans were examined to determine whether accurate interspecies predictions of radiation-induced mortality could be achieved. The analyses revealed that (1) days of life lost per unit dose can be estimated for a species even without information on radiation effects in that species, and (2) accurate predictions of age-specific radiation-induced mortality in beagles and the atomic bomb survivors can be obtained from a dose-response model for comparably exposed mice. These findings illustrate the value of comparative mortality analyses and the relevance of animal data to the study of human health effects.

          Related collections

          Author and article information

          Journal
          Radiat. Res.
          Radiation research
          0033-7587
          0033-7587
          Aug 2003
          : 160
          : 2
          Affiliations
          [1 ] The Donald W. Reynolds Department of Geriatric Medicine, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma 73190, USA. bruce@src.uchicago.edu
          Article
          12859226
          da23b4eb-ef50-47cd-83df-0b4531509dcc
          History

          Non-NASA Center,NASA Discipline Radiation Health

          Comments

          Comment on this article