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      Gene expression alterations in prostate cancer predicting tumor aggression and preceding development of malignancy.

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          Abstract

          The incidence of prostate cancer is frequent, occurring in almost one-third of men older than 45 years. Only a fraction of the cases reach the stages displaying clinical significance. Despite the advances in our understanding of prostate carcinogenesis and disease progression, our knowledge of this disease is still fragmented. Identification of the genes and patterns of gene expression will provide a more cohesive picture of prostate cancer biology.

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          Author and article information

          Journal
          J Clin Oncol
          Journal of clinical oncology : official journal of the American Society of Clinical Oncology
          American Society of Clinical Oncology (ASCO)
          0732-183X
          0732-183X
          Jul 15 2004
          : 22
          : 14
          Affiliations
          [1 ] University of Pittsburgh Cancer Institute and Department of Pathology, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
          Article
          22/14/2790
          10.1200/JCO.2004.05.158
          15254046
          da65feaa-02cc-463b-a06c-572127892606
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