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      Poster Communications

      British Journal of Pharmacology
      Wiley-Blackwell

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          The use of analogue scales in rating subjective feelings

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            Ligand: a versatile computerized approach for characterization of ligand-binding systems.

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              Some quantitative uses of drug antagonists.

              Various applications of pA(x) measurements are discussed based on the hypothesis that drugs and drug antagonists compete for receptors according to the mass law. Examples are given illustrating the use of pA(x) measurements to identify agonists which act on the same receptors and to compare the receptors of different tissues. Tests of competitive and noncompetitive antagonism are considered in relation to the antagonisms acetylcholine-atropine, histamine-atropine and acetylcholine-cinchonidine. A new measure, pA(h), is introduced to express the activity of unsurmountable antagonists.
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                Author and article information

                Journal
                British Journal of Pharmacology
                Wiley-Blackwell
                00071188
                March 1985
                March 1985
                : 84
                :
                : 78P-202P
                Article
                10.1111/j.1476-5381.1985.tb16985.x
                da978c6a-8b47-4603-b798-9dc0cc3e59b0
                © 1985

                http://doi.wiley.com/10.1002/tdm_license_1.1

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