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      Glutathione catalysis and the reaction mechanisms of glutathione-dependent enzymes.

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      Biochimica et biophysica acta
      Elsevier BV

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          Abstract

          Glutathione-dependent catalysis is a metabolic adaptation to chemical challenges encountered by all life forms. In the course of evolution, nature optimized numerous mechanisms to use glutathione as the most versatile nucleophile for the conversion of a plethora of sulfur-, oxygen- or carbon-containing electrophilic substances.

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          Author and article information

          Journal
          Biochim Biophys Acta
          Biochimica et biophysica acta
          Elsevier BV
          0006-3002
          0006-3002
          May 2013
          : 1830
          : 5
          Affiliations
          [1 ] Department of Parasitology, Ruprecht-Karls University, Heidelberg, Germany. marcel.deponte@gmx.de
          Article
          S0304-4165(12)00273-5
          10.1016/j.bbagen.2012.09.018
          23036594
          da9f5bca-ab1f-46cb-806b-986d4fbd344c
          Copyright © 2012 Elsevier B.V. All rights reserved.
          History

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