Blog
About

5
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found

      Risk Factors by Onset Age in Multiple Sclerosis

      a , b , c

      Neuroepidemiology

      S. Karger AG

      Multiple sclerosis, Onset age, Risk factors

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Some investigators have suggested that there are different forms of multiple sclerosis (MS) based on onset age, and that each has a different etiology. 173 Canadian MS patients were matched to controls on age, gender, race and risk zone prior to age 15. Data were collected on: age at onset, gender, initial symptom, disability level, residence history and family background. Three onset age subgroups (early, intermediate and late) were derived. Matched-pair logistic regression analysis indicated that rural residence, use of well water and an MS family history distinguished between patients and controls overall, but showed no significant interaction with onset age. A family history of diabetes distinguished between patients and controls with evidence of age interaction, in that this risk factor decreased in importance as onset age increased.

          Related collections

          Author and article information

          Journal
          NED
          Neuroepidemiology
          10.1159/issn.0251-5350
          Neuroepidemiology
          S. Karger AG
          0251-5350
          1423-0208
          1991
          1991
          12 April 1991
          : 10
          : 1
          : 9-17
          Affiliations
          a Faculty of Rehabilitation Medicine, University of Alberta, Edmonton; b Department of Health Administration, University of Toronto; c Multiple Sclerosis Patient Care and Research Clinic, University of Alberta, Edmonton, Canada
          Article
          110241 Neuroepidemiology 1991;10:9–17
          10.1159/000110241
          2062417
          © 1991 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 9
          Categories
          Original Papers

          Comments

          Comment on this article