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      Hypertension and Its Associated Factors Among Type 2 Diabetes Mellitus Patients at Debre Tabor General Hospital, Northwest Ethiopia

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          Abstract

          Background

          Type 2 diabetes mellitus (T2DM) is associated with a high risk of early mortality and morbidity from hypertension. Even though Ethiopia is Africa’s first country among the top five in the prevalence of DM, there is a paucity of data on hypertension and its associated factors among patients with type 2 diabetes mellitus. Therefore, this study aimed to determine the prevalence and associated factors of hypertension among type 2 diabetes mellitus patients at Debre Tabor General Hospital, 2019.

          Methods and Materials

          An institution-based cross-sectional study was employed on 378 T2DM patients. Data were collected using an interviewer-administered questionnaire and analyzed by Stata 14. A multivariable logistic regression model was used to identify associated factors of hypertension among T2DM patients. Associated factors were declared at p < 0.05.

          Results

          The prevalence of hypertension among T2DM patients was 59.5% (95% CI: 54.5–64.5). Stage 1 hypertension was the most common (30.95%). The odds of hypertension was higher among age group of 50–60 years (adjusted odds ratio (AOR)=2.5, 95% confidence interval (CI) (1.27–4.90)), patients from urban area (AOR = 2.8, 95% CI (1.08–7.18)), with longer duration of T2DM (AOR =1.16, 95% CI (1.08–1.25)), with BMI ≥25 kg/m 2 (AOR = 3.2, 95% CI (1.71–5.96)), with poor glycemic control (AOR = 3.0, 95% CI (1.75–5.19)), and patients who were current cigarette smokers (AOR = 3.8, 95% CI (1.98–14.96)).

          Conclusion

          The prevalence of hypertension is high and the majority have poor blood pressure control. Hence, DM care providers and other health sector stakeholders have to work in collaboration to prevent it through designing appropriate strategies especially for those at higher risk of developing hypertension.

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          Most cited references53

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          Urbanisation and health in China

          Summary China has seen the largest human migration in history, and the country's rapid urbanisation has important consequences for public health. A provincial analysis of its urbanisation trends shows shifting and accelerating rural-to-urban migration across the country and accompanying rapid increases in city size and population. The growing disease burden in urban areas attributable to nutrition and lifestyle choices is a major public health challenge, as are troubling disparities in health-care access, vaccination coverage, and accidents and injuries in China's rural-to-urban migrant population. Urban environmental quality, including air and water pollution, contributes to disease both in urban and in rural areas, and traffic-related accidents pose a major public health threat as the country becomes increasingly motorised. To address the health challenges and maximise the benefits that accompany this rapid urbanisation, innovative health policies focused on the needs of migrants and research that could close knowledge gaps on urban population exposures are needed.
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            Diabetes and Hypertension: A Position Statement by the American Diabetes Association

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              Sodium Intake and Hypertension

              The close relationship between hypertension and dietary sodium intake is widely recognized and supported by several studies. A reduction in dietary sodium not only decreases the blood pressure and the incidence of hypertension, but is also associated with a reduction in morbidity and mortality from cardiovascular diseases. Prolonged modest reduction in salt intake induces a relevant fall in blood pressure in both hypertensive and normotensive individuals, irrespective of sex and ethnic group, with larger falls in systolic blood pressure for larger reductions in dietary salt. The high sodium intake and the increase in blood pressure levels are related to water retention, increase in systemic peripheral resistance, alterations in the endothelial function, changes in the structure and function of large elastic arteries, modification in sympathetic activity, and in the autonomic neuronal modulation of the cardiovascular system. In this review, we have focused on the effects of sodium intake on vascular hemodynamics and their implication in the pathogenesis of hypertension.
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                Author and article information

                Journal
                Diabetes Metab Syndr Obes
                Diabetes Metab Syndr Obes
                DMSO
                dmso
                Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy
                Dove
                1178-7007
                13 May 2020
                2020
                : 13
                : 1621-1631
                Affiliations
                [1 ]Department of Human Physiology, College of Medicine and Health Sciences, University of Gondar , Gondar, Ethiopia
                Author notes
                Correspondence: Yonas Akalu Department of Human Physiology, College of Medicine and Health Sciences, University of Gondar , Gondar,P.O. Box 196, Ethiopia Tel +251 918318230 Email yonasakalu21@gmail.com
                Author information
                http://orcid.org/0000-0002-0914-7768
                http://orcid.org/0000-0001-8984-1495
                Article
                254537
                10.2147/DMSO.S254537
                7231788
                32494180
                db7384bb-a6c2-4b6b-80d6-7e7e96027d21
                © 2020 Akalu and Belsti.

                This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License ( http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms ( https://www.dovepress.com/terms.php).

                History
                : 19 March 2020
                : 30 April 2020
                Page count
                Figures: 1, Tables: 2, References: 69, Pages: 11
                Categories
                Original Research

                Endocrinology & Diabetes
                hypertension,associated factors,type 2 diabetes mellitus,ethiopia
                Endocrinology & Diabetes
                hypertension, associated factors, type 2 diabetes mellitus, ethiopia

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