Sagital abdominal diameter, but not waist circumference is strongly associated with glycemia, triacilglycerols and HDL-C levels in overweight adults

There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

Abstract

Aim: To correlate the sagittal abdominal diameter (SAD) and waist circumference (WC) with metabolic syndrome-associated abnormalities in adults. Methods: This cross-sectional study included onehundred twelve adults (M = 27, F = 85) aging 54.0 ± 11.2 yrs and average body mass index (BMI) of 30.5 ± 9.0 kg/m². The assessment included blood pressure, plasma and anthropometric measurements. Results: In both men and female, SAD and WC were associated positively with body fat% (r = 0.53 vs r = 0.55), uric acid (r = 0.45 vs r = 0.45), us-PCR (r = 0.50 vs r = 0.44), insulin (r = 0.89 vs r = 0.75), insulin resistance HOMA-IR (r = 0.86 vs r = 0.65), LDL-ox (r = 0.51 vs r = 0.28), GGT (r = 0.70 vs r = 0.61), and diastolic blood pressure (r = 0.35 vs r = 0.33), and negatively with insulin sensibility QUICKI (r = -0.89 vs r = -0.82) and total cholesterol/TG ratio (r = -0.40 vs r = -0.22). Glycemia, TG, and HDL-c were associated significantly only with SAD (r = 0.31; r = 39, r = -0.43, respectively). Conclusion: Though the SAD and WC were associated with numerous metabolic abnormalities, only SAD correlated with dyslipidemia (TG and HDL-c) and hyperglycemia (glycemia).

Translated abstract

Objetivo: Correlacionar el diámetro abdominal sagital (DAS) y la circunferencia de la cintura (CC) con las anomalías asociadas al síndrome metabólico en adultos. Métodos: Este estudio transversal incluyó a 112 adultos (H = 27, M = 85) con edad de 54,0 ± 11,2 años y un promedio de índice de masa corporal (IMC) de 30,5 ± 9,0 kg/m². La evaluación incluía la presión sanguínea y medidas plasmáticas y antropométricas. Resultados: Tanto en hombres como mujeres, DAS y CC se asociaban positivamente con el % grasa corporal (r = 0,53 vs r = 0,55), el ácido úrico (r = 0,45 vs r = 0,45), la us-PCR (r = 0,50 vs r = 0,44), la insulina (r = 0,89 vs r = 0,75), la resistencia a la insulina HOMA-IR (r = 0,86 vs r = 0,65), la LDL-ox (r = 0,51 vs r = 0,28), GGT (r = 0,70 vs r = 0,61), y la presión sanguínea diastólica (r = 0,35 vs r = 0,33), y negativamente con la sensibilidad a la insulina QUICKI (r = -0,89 vs r = -0,82) y el cociente colesterol total/TG (r = -0,40 vs r = -0,22). La glucemia, los TG, y la HDL-c se asociaban significativamente sólo con DAS (r = 0,31; r = 0,39, r = -0,43, respectivamente). Conclusión: Aunque DAS y CC se asociaban con numerosas anomalías metabólicas, sólo DAS se correlacionaba con la dislipemia (TG y HDL-c) y la hiperglucemia (glucemia).

Related collections

Most cited references 47

Record: found
Abstract: found
Article: not found

C-Reactive protein, a sensitive marker of inflammation, predicts future risk of coronary heart disease in initially healthy middle-aged men: results from the MONICA (Monitoring Trends and Determinants in Cardiovascular Disease) Augsburg Cohort Study, 1984 to 1992.

W. Koenig, M Sund, M. Fröhlich … (1999)

Inflammatory reactions in coronary plaques play an important role in the pathogenesis of acute atherothrombotic events; inflammation elsewhere is also associated with both atherogenesis generally and its thrombotic complications. Recent studies indicate that systemic markers of inflammation can identify subjects at high risk of coronary events. We used a sensitive immunoradiometric assay to examine the association of serum C-reactive protein (CRP) with the incidence of first major coronary heart disease (CHD) event in 936 men 45 to 64 years of age. The subjects, who were sampled at random from the general population, participated in the first MONICA Augsburg survey (1984 to 1985) and were followed for 8 years. There was a positive and statistically significant unadjusted relationship, which was linear on the log-hazards scale, between CRP values and the incidence of CHD events (n=53). The hazard rate ratio (HRR) of CHD events associated with a 1-SD increase in log-CRP level was 1.67 (95% CI, 1.29 to 2. 17). After adjustment for age, the HRR was 1.60 (95% CI, 1.23 to 2. 08). Adjusting further for smoking behavior, the only variable selected from a variety of potential confounders by a forward stepping process with a 5% change in the relative risk of CRP as the selection criterion, yielded an HRR of 1.50 (95% CI, 1.14 to 1.97). These results confirm the prognostic relevance of CRP, a sensitive systemic marker of inflammation, to the risk of CHD in a large, randomly selected cohort of initially healthy middle-aged men. They suggest that low-grade inflammation is involved in pathogenesis of atherosclerosis, especially its thrombo-occlusive complications.

0 comments Cited 212 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Relationship of C-reactive protein to risk of cardiovascular disease in the elderly. Results from the Cardiovascular Health Study and the Rural Health Promotion Project.

Russell P Tracy, Rozenn N. Lemaitre, Bruce M. Psaty … (1997)

Markers of inflammation, such as C-reactive protein (CRP), are related to risk of cardiovascular disease (CVD) events in those with angina, but little is known about individuals without prevalent clinical CVD. We performed a prospective, nested case-control study in the Cardiovascular Health Study (CHS; 5201 healthy elderly men and women). Case subjects (n = 146 men and women with incident CVD events including angina, myocardial infarction, and death) and control subjects (n = 146) were matched on the basis of sex and the presence or absence of significant subclinical CVD at baseline (average follow-up, 2.4 years). In women but not men, the mean CRP level was higher for case subjects than for control subjects (P < or = .05). In general, CRP was higher in those with subclinical disease. Most of the association of CRP with female case subjects versus control subjects was in the subgroup with subclinical disease; 3.33 versus 1.90 mg/L, P < .05, adjusted for age and time of follow-up. Case-control differences were greatest when the time between baseline and the CVD event was shortest. The strongest associations were with myocardial infarction, and there was an overall odds ratio for incident myocardial infarction for men and women with subclinical disease (upper quartile versus lower three quartiles) of 2.67 (confidence interval [CI] = 1.04 to 6.81), with the relationship being stronger in women (4.50 [CI = 0.97 to 20.8]) than in men (1.75 [CI = 0.51 to 5.98]). We performed a similar study in the Rural Health Promotion Project, in which mean values of CRP were higher for female case subjects than for female control subjects, but no differences were apparent for men. Comparing the upper quintile with the lower four, the odds ratio for CVD case subjects was 2.7 (CI = 1.10 to 6.60). In conclusion, CRP was associated with incident events in the elderly, especially in those with subclinical disease at baseline.

0 comments Cited 67 times – based on 0 reviews      Review now

Bookmark

Record: found
Abstract: found
Article: not found

Four-component model for the assessment of body composition in humans: comparison with alternative methods, and evaluation of the density and hydration of fat-free mass.

M Ann Laskey, Evelin Elia, W A Coward … (1992)

1. Body composition was assessed in 28 healthy subjects (body mass index 20-28 kg/m2) by dual-energy X-ray absorptiometry, deuterium dilution, densitometry, 40K counting and four prediction methods (skinfold thickness, bioelectrical impedance, near-i.r. interactance and body mass index). Three- and four-component models of body composition were constructed from combinations of the reference methods. The results of all methods were compared. Precision was evaluated by analysis of propagation of errors. The density and hydration fraction of the fat-free mass were determined. 2. From the precision of the basic measurements, the propagation of errors for the estimation of fat (+/- SD) by the four-component model was found to be +/- 0.54 kg, by the three-component model, +/- 0.49 kg, by deuterium dilution, +/- 0.62 kg, and by densitometry, +/- 0.78 kg. Precision for the measurement of the density and hydration fraction of fat-free mass was +/- 0.0020 kg/l and +/- 0.0066, respectively. 3. The agreement between reference methods was generally better than between reference and alternative methods. Dual-energy X-ray absorptiometry predicted three- and four-component model body composition slightly less well than densitometry or deuterium dilution (both of which greatly influence these multi-component models). 4. The hydration fraction of fat-free mass was calculated to be 0.7382 +/- 0.0213 (range 0.6941-0.7837) and the density of fat-free mass was 1.1015 +/- 0.0073 kg/l (range 1.0795-1.1110 kg/l), with no significant difference between men and women for either. 5. The results suggest that the three- and four-component models are not compromised by errors arising from individual techniques.(ABSTRACT TRUNCATED AT 250 WORDS)