Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
9
May
2016
Publication date Collection: 2016
Volume: 11
Issue: 5
Electronic Location Identifier: e0155107
Affiliations
[1
]Departments of Orthopaedic Surgery, Albert Einstein College of Medicine and Montefiore
Medical Center, Bronx, NY, United States of America
[2
]Department of Neuroscience, Albert Einstein College of Medicine and Montefiore Medical
Center, Bronx, NY, United States of America
[3
]Department of Urology, Albert Einstein College of Medicine and Montefiore Medical
Center, Bronx, NY, United States of America
[4
]Laboratories of Musculoskeletal Orthopedic Research at Einstein-Montefiore (MORE),
Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY, United
States of America
[5
]Department of Biomedical Engineering, City College of New York, New York, NY, United
States of America
University of California Davis, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Conceived and designed the experiments: ZS SOS MMT. Performed the experiments: ZS
SM SOS MMT. Analyzed the data: ZS SOS MMT. Contributed reagents/materials/analysis
tools: MMT SOS DCS. Wrote the paper: ZS MBS DCS SOS MMT.
Author information
Article
Publisher ID:
PONE-D-16-00489
DOI: 10.1371/journal.pone.0155107
PMC ID: 4861344
PubMed ID: 27159053
SO-VID: dba9b825-0013-4ae8-8602-140f9efd2a7a
Copyright © © 2016 Seref-Ferlengez et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000062, National Institute of Diabetes and Digestive and Kidney Diseases;
Award ID: DK091466
Award Recipient
:
Mia M. Thi
Funded by: funder-id http://dx.doi.org/10.13039/100000062, National Institute of Diabetes and Digestive and Kidney Diseases;
Award ID: DK081435
Award Recipient
:
Sylvia O. Suadicani
Funded by: funder-id http://dx.doi.org/10.13039/100000069, National Institute of Arthritis and Musculoskeletal and Skin Diseases;
Award ID: AR057139, AR041210
Award Recipient
:
Mitchell B. Schaffler
The authors thank Dr. Lynda Bonewald (University of Missouri-Kansas City) for providing
MLO-Y4 cells. This work was supported by the National Institutes of Health National
Institute of Diabetes and Digestive and Kidney Disease [DK091466 (to MMT, SOS and
ZS), DK081435 (to SOS and MMT)], the National Institute of Arthritis and Musculoskeletal
and Skin Diseases [AR057139 (to MBS, DCS and MMT) and AR041210 (to MBS)], and equipment
from a shared instrumentation grant from the National Institutes of Health (S10 RR020949).
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Osteocytes
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Osteocytes
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Osteocytes
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Monosaccharides
Subject:
Glucose
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Carbohydrates
Subject:
Monosaccharides
Subject:
Glucose
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Cellular Types
Subject:
Animal Cells
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Connective Tissue Cells
Subject:
Osteoblasts
Subject:
Biology and Life Sciences
Subject:
Cell Biology
Subject:
Signal Transduction
Subject:
Cell Signaling
Subject:
Glucose Signaling
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Endocrine Disorders
Subject:
Diabetes Mellitus
Subject:
Medicine and Health Sciences
Subject:
Metabolic Disorders
Subject:
Diabetes Mellitus
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Chemical Compounds
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Mannitol
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Organic Chemistry
Subject:
Organic Compounds
Subject:
Alcohols
Subject:
Mannitol
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Bone
Subject:
Bone Density
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Endocrinology
Subject:
Diabetic Endocrinology
Subject:
Insulin
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Insulin