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      Knowledge about Fibromyalgia in Fibromyalgia Patients and Its Relation to HRQoL and Physical Activity

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          Fibromyalgia (FM) affects 2.40% of the Spanish population and its most widespread treatment has been the combination of patient education, pain coping strategies and exercise, in this sense, with respect to patient education, few studies have tried to see the relationship between education in FM with an improvement in FM. Therefore, the aim of this study was to know the level of knowledge about FM among patients in Extremadura, to explore the relationship between knowledge of FM and health-related quality of life (HRQoL), and to analyze the relationship between knowledge of physical activity in FM and the practice of physical activity. For this purpose, 121 women with a mean age of 55.06 years were evaluated. It was found that 10% of these women had low knowledge of FM, 49% medium and 41% high. It was also found that the level of knowledge of physical activity was only weakly related to HRQOL and body pain. Thus, it was concluded that the level of knowledge about FM of patients in Extremadura was medium-high and that there was a weak relationship between knowledge about physical activity in FM and HRQOL. However, no relationship was found between knowledge of physical activity in FM and the practice of physical activity.

          Abstract

          Introduction: Fibromyalgia (FM) affects 2.40% of the Spanish population. The most widespread treatment has been the combination of patient education, pain coping strategies and exercise. With regard to patient education, there are few previous studies on the efficacy of relating FM education in isolation with an improvement in FM, although there are some studies that report that health education programs could modify the perception of quality of life and improve pain. Objectives: the aim was to find out the level of knowledge about FM among patients in Extremadura, to explore the relationship between knowledge of FM and Health-Related Quality of Life (HRQoL) and to analyze the relationship between knowledge of physical activity in FM and the practice of physical activity. Methods: A single-measure cross-sectional study was carried out with 121 women with a mean age of 55.06 (±9.93) years. The following questionnaires were used: Fibromyalgia Knowledge Questionnaire (FKQ); SF12v2 (Short-Form Health Survey); and EURO-QOL-5D-5L (EQ-5D-5L). Results: regarding the level of knowledge of the participants about FM, it was found that 10% had a low knowledge, 49% medium and 41% high. In relation to the associations between the level of knowledge and HRQoL, a weak correlation between EQ-5D-5L and the FKQ in the domain of physical activity (r = 0.243) were found. Conclusions: it can be concluded that the level of knowledge about FM of the patients from Extremadura was medium-high and that there is a direct weak relationship between knowledge about physical activity in FM and HRQoL. However, no association was found between knowledge of physical activity in FM and the practice of physical activity.

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          A 12-Item Short-Form Health Survey: construction of scales and preliminary tests of reliability and validity.

          Regression methods were used to select and score 12 items from the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) to reproduce the Physical Component Summary and Mental Component Summary scales in the general US population (n=2,333). The resulting 12-item short-form (SF-12) achieved multiple R squares of 0.911 and 0.918 in predictions of the SF-36 Physical Component Summary and SF-36 Mental Component Summary scores, respectively. Scoring algorithms from the general population used to score 12-item versions of the two components (Physical Components Summary and Mental Component Summary) achieved R squares of 0.905 with the SF-36 Physical Component Summary and 0.938 with SF-36 Mental Component Summary when cross-validated in the Medical Outcomes Study. Test-retest (2-week)correlations of 0.89 and 0.76 were observed for the 12-item Physical Component Summary and the 12-item Mental Component Summary, respectively, in the general US population (n=232). Twenty cross-sectional and longitudinal tests of empirical validity previously published for the 36-item short-form scales and summary measures were replicated for the 12-item Physical Component Summary and the 12-item Mental Component Summary, including comparisons between patient groups known to differ or to change in terms of the presence and seriousness of physical and mental conditions, acute symptoms, age and aging, self-reported 1-year changes in health, and recovery for depression. In 14 validity tests involving physical criteria, relative validity estimates for the 12-item Physical Component Summary ranged from 0.43 to 0.93 (median=0.67) in comparison with the best 36-item short-form scale. Relative validity estimates for the 12-item Mental Component Summary in 6 tests involving mental criteria ranged from 0.60 to 107 (median=0.97) in relation to the best 36-item short-form scale. Average scores for the 2 summary measures, and those for most scales in the 8-scale profile based on the 12-item short-form, closely mirrored those for the 36-item short-form, although standard errors were nearly always larger for the 12-item short-form.
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            Biostatistical Analysis

            Designed for one/two-semester, junior/graduate-level courses in Biostatistics, Biometry, Quantitative Biology, or Statistics, the latest edition of this best-selling biostatistics text is both comprehensive and easy to read. It provides a broad and practical overview of the statistical analysis methods used by researchers to collect, summarize, analyze, and draw conclusions from biological research data. The Fourth Edition can serve as either an introduction to the discipline for beginning students or a comprehensive procedural reference for today's practitioners.
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              Interim scoring for the EQ-5D-5L: mapping the EQ-5D-5L to EQ-5D-3L value sets.

              A five-level version of the EuroQol five-dimensional (EQ-5D) descriptive system (EQ-5D-5L) has been developed, but value sets based on preferences directly elicited from representative general population samples are not yet available. The objective of this study was to develop values sets for the EQ-5D-5L by means of a mapping ("crosswalk") approach to the currently available three-level version of the EQ-5D (EQ-5D-3L) values sets. The EQ-5D-3L and EQ-5D-5L descriptive systems were coadministered to respondents with conditions of varying severity to ensure a broad range of levels of health across EQ-5D questionnaire dimensions. We explored four models to generate value sets for the EQ-5D-5L: linear regression, nonparametric statistics, ordered logistic regression, and item-response theory. Criteria for the preferred model included theoretical background, statistical fit, predictive power, and parsimony. A total of 3691 respondents were included. All models had similar fit statistics. Predictive power was slightly better for the nonparametric and ordered logistic regression models. In considering all criteria, the nonparametric model was selected as most suitable for generating values for the EQ-5D-5L. The nonparametric model was preferred for its simplicity while performing similarly to the other models. Being independent of the value set that is used, it can be applied to transform any EQ-5D-3L value set into EQ-5D-5L index values. Strengths of this approach include compatibility with three-level value sets. A limitation of any crosswalk is that the range of index values is restricted to the range of the EQ-5D-3L value sets. Copyright © 2012 International Society for Pharmacoeconomics and Outcomes Research (ISPOR). Published by Elsevier Inc. All rights reserved.
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                Author and article information

                Contributors
                Role: Academic Editor
                Role: Academic Editor
                Journal
                Biology (Basel)
                Biology (Basel)
                biology
                Biology
                MDPI
                2079-7737
                16 July 2021
                July 2021
                : 10
                : 7
                : 673
                Affiliations
                [1 ]Health, Economy, Motricity and Education Research Group (HEME), Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain; mamendozam@ 123456unex.es (M.M.-M.); judgm@ 123456hotmail.com (J.G.-M.); jocalzada@ 123456alumnos.unex.es (J.I.C.-R.)
                [2 ]Motor Control Research Group, Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain
                [3 ]BioErgon Research Group, Faculty of Sport Sciences, University of Extremadura, 10003 Caceres, Spain; mrodal@ 123456unex.es
                [4 ]Universidad Autónoma de Chile, Talca 3467987, Chile; miguel.garcia@ 123456uautonoma.cl
                Author notes
                [* ]Correspondence: jesusmorenas@ 123456unex.es
                Author information
                https://orcid.org/0000-0001-9502-5486
                https://orcid.org/0000-0003-1349-2203
                https://orcid.org/0000-0003-1736-0996
                Article
                biology-10-00673
                10.3390/biology10070673
                8301415
                dc0c345b-b033-45ff-aab8-e0c7619bebb9
                © 2021 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( https://creativecommons.org/licenses/by/4.0/).

                History
                : 03 June 2021
                : 14 July 2021
                Categories
                Article

                hrqol,knowledge,physical activity,rheumatic diseases,women
                hrqol, knowledge, physical activity, rheumatic diseases, women

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