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      Gene polymorphisms of OPRM1 A118G and ABCB1 C3435T may influence opioid requirements in Chinese patients with cancer pain.

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          Abstract

          Polymorphisms of OPRM1 A118G and ABCB1 C3435T have been suggested to contribute to inter-individual variability regarding pain sensitivity, opioid usage, tolerance and dependence and incidence of adverse effects in patients with chronic pain. This study aimed to investigate the association of both two polymorphisms with opioid requirements in Chinese patients with cancer pain.

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          Author and article information

          Journal
          Asian Pac. J. Cancer Prev.
          Asian Pacific journal of cancer prevention : APJCP
          2476-762X
          1513-7368
          2013
          : 14
          : 5
          Affiliations
          [1 ] Department of Oncology, Shanghai Third People's Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
          Article
          23803057

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