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      Isolation as a strategy for controlling the transmission of hepatitis C virus (HCV) infection in haemodialysis units.

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          Abstract

          The hepatitis C virus (HCV) infection affects about 2% of the world's population and can cause chronic liver infection and persistent long-term sequelae such as cirrhosis and liver cancer.The prevalence of HCV infection among people on haemodialysis is often higher than the general population. The virus is easily transmitted parenterally, and blood transfusions have previously played a significant role in transmission; however, erythropoietin therapy has reduced the need for transfusions, and coupled with improved screening of donated blood, has significantly decreased transmission by transfusion. Although control of hospital-acquired infection has improved with the advent of biosafety measures, stopping HCV transmission in haemodialysis units remains challenging.Isolating people infected with HCV involves physical separation from others to limit direct or indirect transmission and includes a number of strategies during dialysis. The evidence for isolating people infected with HCV during haemodialysis is sparse with some inconsistencies.

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          Author and article information

          Journal
          Cochrane Database Syst Rev
          The Cochrane database of systematic reviews
          Wiley-Blackwell
          1469-493X
          1361-6137
          Aug 11 2016
          : 8
          Affiliations
          [1 ] Universidad Peruana Cayetano Heredia, Lima, Peru, 031.
          Article
          10.1002/14651858.CD006420.pub2
          27513591

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