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Limited therapies are offered for large hepatocellular carcinoma (HCC). It carries
dismal prognosis and efforts tried changing its management from a palliative to a
curative mode. Transarterial chemoembolization (TACE) is a palliative procedure that
may have survival benefit if compared to non-management of large lesions. Microwave
ablation (MWA) has emerged as a relatively new technique with promise of larger and
faster ablation. We aim to evaluate the efficacy and safety of percutaneous MWA versus
TACE for large tumors (5-7 cm) and to assess their effects on local tumor progression