Tourette syndrome (TS) is a heritable neuropsychiatric disorder commonly complicated
by obsessions and compulsions, but defined by frequent unwanted movements (motor tics)
and vocalizations (phonic tics) that develop in childhood or adolescence. In recent
years, research on TS has progressed rapidly on several fronts. Inspired by the Fifth
International Scientific Symposium on Tourette Syndrome, the articles in this special
issue review advances in the phenomenology, epidemiology, genetics, pathophysiology,
and treatment of TS.