Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
8
August
2016
Publication date Collection: 2016
Volume: 11
Issue: 8
Electronic Location Identifier: e0160457
Affiliations
[1
]Department of Biochemistry, Stanford University, Stanford, California, 94305, United
States of America
[2
]Leiden Institute of Chemistry, Leiden University, Leiden, 2333 CC, the Netherlands
[3
]Departments of Chemical Engineering and Chemistry, Stanford University, Stanford,
California, 94305, United States of America
[4
]Stanford ChEM-H (Chemistry, Engineering, and Medicine for Human Health), Stanford
University, Stanford, California, 94305, United States of America
Oak Ridge National Laboratory, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
-
Conceived and designed the experiments: SNS RNS DH.
-
Performed the experiments: SNS RNS.
-
Analyzed the data: SNS RNS.
-
Wrote the paper: SNS RNS DH.
Article
Publisher ID:
PONE-D-16-16517
DOI: 10.1371/journal.pone.0160457
PMC ID: 4976970
PubMed ID: 27501145
SO-VID: dcd0f658-1809-41a1-aebc-19e841120c22
Copyright © © 2016 van Schie et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: GM049243
Award Recipient
:
Daniel Herschlag
Funded by: funder-id http://dx.doi.org/10.13039/100000002, National Institutes of Health;
Award ID: 5 T32 GM007276
Award Recipient
:
Raghuvir N. Sengupta
This work was supported by National Institutes of Health grant GM049243 (
https://www.nih.gov/) to DH, and National Institutes of Health Training Grant 5 T32 GM007276 (
https://www.nih.gov/) to RNS. The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Enzymology
Subject:
Enzymes
Subject:
Ribozymes
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Proteins
Subject:
Enzymes
Subject:
Ribozymes
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Nucleic Acids
Subject:
RNA
Subject:
Ribozymes
Subject:
Biology and Life Sciences
Subject:
Organisms
Subject:
Protozoans
Subject:
Ciliate Protozoans
Subject:
Tetrahymena
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Physical Chemistry
Subject:
Reaction Dynamics
Subject:
Transition State
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Physical Chemistry
Subject:
Chemical Equilibrium
Subject:
Physical Sciences
Subject:
Physics
Subject:
Thermodynamics
Subject:
Biology and Life Sciences
Subject:
Computational Biology
Subject:
Genome Complexity
Subject:
Introns
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Genomics
Subject:
Genome Complexity
Subject:
Introns
Subject:
Biology and life sciences
Subject:
Molecular biology
Subject:
Macromolecular structure analysis
Subject:
RNA structure
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
RNA
Subject:
RNA structure
Subject:
Physical Sciences
Subject:
Chemistry
Subject:
Catalysis