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      Disease proteomics.

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      Nature
      Springer Science and Business Media LLC

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          Abstract

          The sequencing of the human genome and that of numerous pathogens has opened the door for proteomics by providing a sequence-based framework for mining proteomes. As a result, there is intense interest in applying proteomics to foster a better understanding of disease processes, develop new biomarkers for diagnosis and early detection of disease, and accelerate drug development. This interest creates numerous opportunities as well as challenges to meet the needs for high sensitivity and high throughput required for disease-related investigations.

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          Author and article information

          Journal
          Nature
          Nature
          Springer Science and Business Media LLC
          0028-0836
          0028-0836
          Mar 13 2003
          : 422
          : 6928
          Affiliations
          [1 ] Department of Pediatrics, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, Michigan 48109, USA. shanash@umich.edu
          Article
          nature01514
          10.1038/nature01514
          12634796
          dd4c8a23-f772-4bfa-9805-8f215dc54c8b
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