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      Structural Basis for Mitral Valve Dysfunction Associated with Ostium Secundum Atrial Septal Defects

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          Abstract

          Mitral valve (MV) specimens obtained at operation from 50 patients with ostium secundum atrial septal defect and associated MV dysfunction were studied macro- and microscopically to evaluate the structural lesions. The functional abnormalities in these patients were isolated mitral stenosis, isolated mitral regurgitation, mitral valve prolapse or mitral stenosis with regurgitation. Post-inflammatory lesions were commonly found in those with mitral stenosis who had a past history of rheumatic fever. Patients with mitral valve prolapse had either post-inflammatory lesions or lesions attributable to hae-modynamic stress but different from the extensive lesions seen in floppy MV syndrome.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1993
          1993
          14 November 2008
          : 82
          : 6
          : 409-414
          Affiliations
          aDepartment of Cardiology and bDivision of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum, Kerala, India
          Article
          175895 Cardiology 1993;82:409–414
          10.1159/000175895
          8402764
          © 1993 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          Congenital Heart Disease

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