For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
38
views
270
references
 Top references
cited by
51
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      253
      similar
       All similar
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Nanoparticles as Anti-Microbial, Anti-Inflammatory, and Remineralizing Agents in Oral Care Cosmetics: A Review of the Current Situation

      review-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Many investigations have pointed out widespread use of medical nanosystems in various domains of dentistry such as prevention, prognosis, care, tissue regeneration, and restoration. The progress of oral medicine nanosystems for individual prophylaxis is significant for ensuring bacterial symbiosis and high-quality oral health. Nanomaterials in oral cosmetics are used in toothpaste and other mouthwash to improve oral healthcare performance. These processes cover nanoparticles and nanoparticle-based materials, especially domains of application related to biofilm management in cariology and periodontology. Likewise, nanoparticles have been integrated in diverse cosmetic produces for the care of enamel remineralization and dental hypersensitivity. This review summarizes the indications and applications of several widely employed nanoparticles in oral cosmetics, and describes the potential clinical implementation of nanoparticles as anti-microbial, anti-inflammatory, and remineralizing agents in the prevention of dental caries, hypersensitivity, and periodontitis.

          Related collections

          Most cited references270

          • Record: found
          • Abstract: found
          • Article: not found

          Review on Zinc Oxide Nanoparticles: Antibacterial Activity and Toxicity Mechanism

          Amna Sirelkhatim, Shahrom Mahmud, Azman Seeni … (2015)
          Antibacterial activity of zinc oxide nanoparticles (ZnO-NPs) has received significant interest worldwide particularly by the implementation of nanotechnology to synthesize particles in the nanometer region. Many microorganisms exist in the range from hundreds of nanometers to tens of micrometers. ZnO-NPs exhibit attractive antibacterial properties due to increased specific surface area as the reduced particle size leading to enhanced particle surface reactivity. ZnO is a bio-safe material that possesses photo-oxidizing and photocatalysis impacts on chemical and biological species. This review covered ZnO-NPs antibacterial activity including testing methods, impact of UV illumination, ZnO particle properties (size, concentration, morphology, and defects), particle surface modification, and minimum inhibitory concentration. Particular emphasize was given to bactericidal and bacteriostatic mechanisms with focus on generation of reactive oxygen species (ROS) including hydrogen peroxide (H2O2), OH− (hydroxyl radicals), and O2 −2 (peroxide). ROS has been a major factor for several mechanisms including cell wall damage due to ZnO-localized interaction, enhanced membrane permeability, internalization of NPs due to loss of proton motive force and uptake of toxic dissolved zinc ions. These have led to mitochondria weakness, intracellular outflow, and release in gene expression of oxidative stress which caused eventual cell growth inhibition and cell death. In some cases, enhanced antibacterial activity can be attributed to surface defects on ZnO abrasive surface texture. One functional application of the ZnO antibacterial bioactivity was discussed in food packaging industry where ZnO-NPs are used as an antibacterial agent toward foodborne diseases. Proper incorporation of ZnO-NPs into packaging materials can cause interaction with foodborne pathogens, thereby releasing NPs onto food surface where they come in contact with bad bacteria and cause the bacterial death and/or inhibition.
          Article 0 comments Cited 839 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            P25-graphene composite as a high performance photocatalyst.

            Hao Zhang, Xiaojun Lv, Yueming Li … (2010)
            Herein we obtained a chemically bonded TiO(2) (P25)-graphene nanocomposite photocatalyst with graphene oxide and P25, using a facile one-step hydrothermal method. During the hydrothermal reaction, both of the reduction of graphene oxide and loading of P25 were achieved. The as-prepared P25-graphene photocatalyst possessed great adsorptivity of dyes, extended light absorption range, and efficient charge separation properties simultaneously, which was rarely reported in other TiO(2)-carbon photocatalysts. Hence, in the photodegradation of methylene blue, a significant enhancement in the reaction rate was observed with P25-graphene, compared to the bare P25 and P25-CNTs with the same carbon content. Overall, this work could provide new insights into the fabrication of a TiO(2)-carbon composite as high performance photocatalysts and facilitate their application in the environmental protection issues.
            Article 0 comments Cited 623 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Silver colloid nanoparticles: synthesis, characterization, and their antibacterial activity.

              Ales Panacek, Libor Kvitek, Robert Prucek … (2006)
              A one-step simple synthesis of silver colloid nanoparticles with controllable sizes is presented. In this synthesis, reduction of [Ag(NH(3))(2)](+) complex cation by four saccharides was performed. Four saccharides were used: two monosaccharides (glucose and galactose) and two disaccharides (maltose and lactose). The syntheses performed at various ammonia concentrations (0.005-0.20 mol L(-1)) and pH conditions (11.5-13.0) produced a wide range of particle sizes (25-450 nm) with narrow size distributions, especially at the lowest ammonia concentrations. The average size, size distribution, morphology, and structure of particles were determined by dynamic light scattering (DLS), transmission electron microscopy (TEM), and UV/Visible absorption spectrophotometry. The influence of the saccharide structure (monosacharides versus disaccharides) on the size of silver particles is briefly discussed. The reduction of [Ag(NH(3))(2)](+) by maltose produced silver particles with a narrow size distribution with an average size of 25 nm, which showed high antimicrobial and bactericidal activity against Gram-positive and Gram-negative bacteria, including highly multiresistant strains such as methicillin-resistant Staphylococcus aureus. Antibacterial activity of silver nanoparticles was found to be dependent on the size of silver particles. A very low concentration of silver (as low as 1.69 mug/mL Ag) gave antibacterial performance.
              Article 0 comments Cited 463 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Journal ID (nlm-ta): Nanomaterials (Basel)
                Journal ID (iso-abbrev): Nanomaterials (Basel)
                Journal ID (publisher-id): nanomaterials
                Title: Nanomaterials
                Publisher: MDPI
                ISSN (Electronic): 2079-4991
                Publication date (Electronic): 13 January 2020
                Publication date Collection: January 2020
                Volume: 10
                Issue: 1
                Electronic Location Identifier: 140
                Affiliations
                [1 ]Laboratory “Systemic Health Care”, University of Lyon, University Claude Bernard Lyon 1, EA4129, 69008 Lyon, France; stephane.viennot@ 123456univ-lyon1.fr (S.V.); denis.bourgeois69@ 123456orange.fr (D.B.)
                [2 ]Department of Oral and Maxillo-facial Sciences, Sapienza University of Rome, 00185 Rome, Italy; livia.ottolenghi@ 123456uniroma1.it
                [3 ]Institut national de Recherche en Agriculture, Alimentation et Environnement (INRAE), Unité de Recherche 1268 Biopolymères Interactions Assemblages (BIA), 44316 Nantes, France; cedric.gaillard@ 123456inra.fr
                Author notes
                [* ]Correspondence: florence.carrouel@ 123456univ-lyon1.fr ; Tel.: +33-4-78-78-57-44
                Author information
                https://orcid.org/0000-0002-6823-1636
                https://orcid.org/0000-0001-7390-4316
                https://orcid.org/0000-0003-4754-2512
                Article
                Publisher ID: nanomaterials-10-00140
                DOI: 10.3390/nano10010140
                PMC ID: 7022934
                PubMed ID: 31941021
                SO-VID: dd8e255a-b10a-4e99-9755-eb126b24da20
                Copyright © © 2020 by the authors.
                License:

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                Date received : 06 December 2019
                Date accepted : 10 January 2020
                Categories
                Subject: Review

                Keywords: nanoparticles,oral cosmetics,toothpaste,mouthwash,biofilm,caries,periodontology,hypersensitivity
                Data availability:
                Keywords: nanoparticles, oral cosmetics, toothpaste, mouthwash, biofilm, caries, periodontology, hypersensitivity

                Comments

                Comment on this article

                scite_

                Similar content253

                See all similar

                Cited by51

                See all cited by

                Most referenced authors3,925

                See all reference authors