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      Epidemiology, management, complications and costs associated with type 2 diabetes in Brazil: a comprehensive literature review

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          Abstract

          Background

          With an estimated 74% of all deaths attributable to non-communicable diseases (NCDs) in 2010, NCDs have become a major health priority in Brazil. The objective of the study was to conduct a comprehensive literature review on diabetes in Brazil; specifically: the epidemiology of type 2 diabetes, the availability of national and regional sources of data (particularly in terms of direct and indirect costs) and health policies for the management of diabetes and its complications.

          Methods

          A literature search was conducted using PubMed to identify articles containing information on diabetes in Brazil. Official documents from the Brazilian government and the World Health Organization, as well as other grey literature and official government websites were also reviewed.

          Results

          From 2006 to 2010, an approximate 20% increase in the prevalence of self-reported diabetes was observed. In 2010, it was estimated that 6.3% of Brazilians aged 18 years or over had diabetes. Diabetes was estimated to be responsible for 278,778 years of potential life lost for every 100,000 people. In 2013, it is estimated that about 7% of patients with diabetes has had one or more of the following complications: diabetic foot ulcers, amputation, kidney disease, and fundus changes. The estimated annual direct cost of diabetes was USD $3.952 billion in 2000; the estimated annual indirect cost was USD $18.6 billion. The two main sources of data on diabetes are the information systems of the Ministry of Health and surveys. In the last few years, the Brazilian Ministry of Health has invested considerably in improving surveillance systems for NCDs as well as implementing specific programmes to improve diagnosis and access to treatment.

          Conclusions

          Brazil has the capacity to address and respond to NCDs due to the leadership of the Ministry of Health in NCD prevention activities, including an integrated programme currently in place for diabetes. Strengthening the surveillance of NCDs is a national priority along with recognising the urgent need to invest in improving the coverage and quality of mortality data. It is also essential to conduct regular surveys of risk factors on a national scale in order to design effective preventive strategies.

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          Most cited references37

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          Políticas sociais no Brasil: descentralização em um Estado federativo

          O artigo analisa o processo de descentralização do Sistema Brasileiro de Proteção Social, identificando sua extensão e variação e os fatores que determinam o formato que este vem assumindo. O objeto da análise é a descentralização de cinco políticas sociais - saúde, habitação, saneamento básico, assistência social e educação fundamental - em seis estados brasileiros - Rio Grande do Sul, Paraná, São Paulo, Bahia, Pernambuco e Ceará. O trabalho examina a importância dos seguintes fatores para explicar a extensão e a variação da descentralização: (a) os atributos estruturais das unidades locais de governo - capacidade econômica, fiscal e administrativa -; (b) os atributos institucionais das políticas - regras constitucionais, requisitos de engenharia operacional e legado das políticas prévias - e (c) os fatores ligados à ação política - relações entre Estado e sociedade e relações intergovernamentais.
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            Apresentação do plano de ações estratégicas para o enfrentamento das doenças crônicas não transmissíveis no Brasil, 2011 a 2022

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              Multicenter study of the prevalence of diabetes mellitus and impaired glucose tolerance in the urban Brazilian population aged 30-69 yr. The Brazilian Cooperative Group on the Study of Diabetes Prevalence.

              To assess the prevalence of diabetes and IGT in the urban adult Brazilian population. We used a two-stage, multicenter, cross-sectional survey in a random sample of 21,847 individuals aged 30-69 yr from nine large cities. Subjects were first screened by FCG. All positive screenees (FCG > or = 5.6 mM/L) and every sixth consecutive negative screenee were administered a 75 g OGTT and classified as diabetic, IGT, or normal (nondiabetic) according to WHO recommendations. OGTT findings from the negative screenees were extrapolated to all negative screenees after adjustments for potential biases. The overall rates were 7.6 and 7.8% for diabetes and IGT, respectively. Men (7.5%) and women (7.6%) had similar rates of diabetes. Similar rates resulted with whites (7.8%) and nonwhites (7.3%). Diabetes prevalence increased from 2.7% in the 30-39-yr age-group to 17.4% in the 60-69-yr age-group. Diabetes was more prevalent among less educated people, but this difference disappeared after adjusting for age. Family history of diabetes was associated with a twofold increase in diabetes prevalence (12.5 vs. 5.8%); the same increase occurred with obesity (11.6 vs. 5.2%). Undiagnosed diabetes accounted for 46% of the total prevalence. Among previously diagnosed cases, 22.3% were not under treatment, 7.9% were on insulin, 40.7% were on oral agents, and 29.1% were on dietary treatment only. Self-reported diabetes prevalence was 0.1, 3.2, and 11.6% in the age groups 70 yr, respectively. The prevalence of diabetes in Brazil is comparable with that of more developed countries, where it is considered a major health problem.
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                Author and article information

                Contributors
                Journal
                Global Health
                Global Health
                Globalization and Health
                BioMed Central
                1744-8603
                2013
                3 December 2013
                : 9
                : 62
                Affiliations
                [1 ]Programa de Pós-graduação em Epidemiologia, Universidade Federal de Pelotas, Rua Marechal Deodoro, 1160 3° piso, Pelotas, RS, Brazil, 96.020-220
                [2 ]LSE Health, London School of Economics and Political Science, London, UK
                [3 ]Department of Social Policy, London School of Economics and Political Science, London, UK
                [4 ]MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
                [5 ]Programa de Pós-Graduação em Organizações e Mercados, Universidade Federal de Pelotas, RS, Brazil
                [6 ]Programa de Pós-graduação em Epidemiologia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
                Article
                1744-8603-9-62
                10.1186/1744-8603-9-62
                4220809
                24299125
                dddd089c-dd25-4f81-a7db-b77929b11f72
                Copyright © 2013 Bertoldi et al.; licensee BioMed Central Ltd.

                This is an open access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 26 June 2013
                : 11 November 2013
                Categories
                Research

                Health & Social care
                diabetes,brazil,costs,epidemiology
                Health & Social care
                diabetes, brazil, costs, epidemiology

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