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      Draft Genome Sequence of the Cellulolytic, Mesophilic, Anaerobic Bacterium Clostridium termitidis Strain CT1112 (DSM 5398)

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          Abstract

          Here, we report the draft genome sequence of Clostridium termitidis strain CT1112 (DSM 5398), a mesophilic, cellulolytic bacterium that can utilize a variety of sugars, as well as pure cellulose, as a sole carbon source; it also synthesizes fermentation end products with potential industrial applications.

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          GenePRIMP: a gene prediction improvement pipeline for prokaryotic genomes.

          We present 'gene prediction improvement pipeline' (GenePRIMP; http://geneprimp.jgi-psf.org/), a computational process that performs evidence-based evaluation of gene models in prokaryotic genomes and reports anomalies including inconsistent start sites, missed genes and split genes. We found that manual curation of gene models using the anomaly reports generated by GenePRIMP improved their quality, and demonstrate the applicability of GenePRIMP in improving finishing quality and comparing different genome-sequencing and annotation technologies.
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            Author and article information

            Journal
            Genome Announc
            Genome Announc
            ga
            ga
            GA
            Genome Announcements
            American Society for Microbiology (1752 N St., N.W., Washington, DC )
            2169-8287
            23 May 2013
            May-Jun 2013
            : 1
            : 3
            : e00281-13
            Affiliations
            Department of Biosystems Engineering, University of Manitoba, Winnipeg, Manitoba, Canada [a ]
            Department of Microbiology, University of Manitoba, Winnipeg, Manitoba, Canada [b ]
            Department of Plant Science, University of Manitoba, Winnipeg, Manitoba, Canada [c ]
            Author notes
            Address correspondence to David B. Levin, david.levin@ 123456ad.umanitoba.ca .
            Article
            genomeA00281-13
            10.1128/genomeA.00281-13
            3662827
            23704187
            ddf5c9ca-ca5b-4135-8a24-4926820c85fb
            Copyright © 2013 Lal et al.

            This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license.

            History
            : 8 April 2013
            : 15 April 2013
            Page count
            Pages: 2
            Categories
            Prokaryotes
            Custom metadata
            May/June 2013
            free

            Genetics
            Genetics

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