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      Calamenenes--aromatic bicyclic sesquiterpenes--from the Indian gorgonian Subergorgia reticulata (Ellis and Solander, 1786).

      Natural product research
      Humans, India, Magnetic Resonance Spectroscopy, Terpenes, administration & dosage

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          Abstract

          Three aromatic sesquiterpene derivatives, (+)-(7R, 10S)-2-methoxy calamenene (1), (+)-(7R, 10S)-2,5-dimethoxy calamenene (2) and (+)-(7R, 10S)-2-methoxy-5-acetoxy calamenene (3) were isolated from the methanol extract of the Indian gorgonian Subergorgia reticulata. Compound 2 has not been previously described in the literature. Compound 3 has not been isolated previously from a natural source. Compounds 1, 2 and 3 showed settlement inhibition activity against cyprids of Balanus amphitrite with EC(50) values of 4.4, 7.8 and 0.03 µg mL(-1), respectively. These compounds also exhibited considerable activity against Artemia nauplii at 50 µg mL(-1), indicative of their potential use as cytotoxic agents.

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          Author and article information

          Journal
          21246444
          10.1080/14786419.2010.495069

          Chemistry
          Humans,India,Magnetic Resonance Spectroscopy,Terpenes,administration & dosage
          Chemistry
          Humans, India, Magnetic Resonance Spectroscopy, Terpenes, administration & dosage

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