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      Cardiovascular, Inflammatory, and Metabolic Consequences of Sleep Deprivation

      , , , ,

      Progress in Cardiovascular Diseases

      Elsevier BV

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          Abstract

          That insufficient sleep is associated with poor attention and performance deficits is becoming widely recognized. Fewer people are aware that chronic sleep complaints in epidemiologic studies have also been associated with an increase in overall mortality and morbidity. This article summarizes findings of known effects of insufficient sleep on cardiovascular risk factors including blood pressure, glucose metabolism, hormonal regulation, and inflammation with particular emphasis on experimental sleep loss, using models of total and partial sleep deprivation, in healthy individuals who normally sleep in the range of 7 to 8 hours and have no sleep disorders. These studies show that insufficient sleep alters established cardiovascular risk factors in a direction that is known to increase the risk of cardiac morbidity.

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          Author and article information

          Journal
          Progress in Cardiovascular Diseases
          Progress in Cardiovascular Diseases
          Elsevier BV
          00330620
          January 2009
          January 2009
          : 51
          : 4
          : 294-302
          Article
          10.1016/j.pcad.2008.10.003
          3403737
          19110131
          © 2009

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