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      Induction therapy with adalimumab plus methotrexate for 24 weeks followed by methotrexate monotherapy up to week 48 versus methotrexate therapy alone for DMARD-naive patients with early rheumatoid arthritis: HIT HARD, an investigator-initiated study.

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          Abstract

          To investigate the long-term effects of induction therapy with adalimumab (ADA) plus methotrexate (MTX) in comparison with placebo (PBO) plus MTX in DMARD-naïve patients with active early rheumatoid arthritis (RA).

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          Author and article information

          Journal
          Ann. Rheum. Dis.
          Annals of the rheumatic diseases
          BMJ
          1468-2060
          0003-4967
          Jun 2013
          : 72
          : 6
          Affiliations
          [1 ] Department of Rheumatology and Clinical Immunology, Charité-Universitätsmedizin Berlin, Berlin, Germany. jacqueline.detert@charite.de
          Article
          annrheumdis-2012-201612
          10.1136/annrheumdis-2012-201612
          22739990
          deafd56b-554b-4dac-b545-db0d9c94dd14
          History

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