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Neural Correlates of Procedural Variants in Cognitive-Behavioral Therapy: A Randomized, Controlled Multicenter fMRI Study
Benjamin Straube ,
Ulrike Lueken ,
Andreas Jansen ,
Carsten Konrad ,
Andrew T. Gloster ,
Alexander L. Gerlach ,
Andreas Ströhle ,
André Wittmann ,
Bettina Pfleiderer ,
Siegfried Gauggel ,
Ulrich Wittchen ,
Volker Arolt ,
Tilo Kircher
July 1 2014
June 19 2014
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Abstract
Cognitive behavioral therapy (CBT) is an effective treatment for panic disorder with
agoraphobia (PD/AG). It is unknown, how variants of CBT differentially modulate brain
networks involved in PD/AG. This study was aimed to evaluate the effects of therapist-guided
(T+) versus self-guided (T-) exposure on the neural correlates of fear conditioning
in PD/AG.