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      Methodology for the Establishment of Growth Standards

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          Abstract

          Providing reference values in the form of percentiles for the assessment of paediatric growth is of great practical importance. Extreme centiles are particularly important in the diagnostic process. On the other hand, their statistical variability is inherently large. When measurements approximate to a normal distribution -as for height – centiles can be obtained more accurately. Otherwise, empirical centiles and/or more refined methods are needed. To exploit the age-dependent nature of centiles, smoothing methods are recommended. Accounting for midparental height as a covariate in the calculation of centiles greatly improves their validity due to an increased sensitivity and specificity.

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          Author and article information

          Journal
          HRE
          Horm Res Paediatr
          10.1159/issn.1663-2818
          Hormone Research in Paediatrics
          S. Karger AG
          978-3-8055-6324-6
          978-3-318-01531-7
          1663-2818
          1663-2826
          1996
          1996
          09 December 2008
          : 45
          : Suppl 2
          : 2-7
          Affiliations
          aAbteilung Biostatistik und bKinderspital, Universität Zurich, Schweiz
          Article
          184840 Horm Res 1996;45:2–7
          10.1159/000184840
          8805038
          © 1996 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 6
          Categories
          Growth Standards

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