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      CARDIOTOXICIDAD POSTERIOR A LA INTOXICACIÓN POR AMITRAZ: REPORTE DE CASO Y REVISIÓN DE LA LITERATURA Translated title: CARDIOTOXICITY FOLLOWING AMITRAZ POISONING: A CASE REPORT AND LITERATURE REVIEW Translated title: CARDIOTOXICIDADE APÓS INTOXICAÇÃO PELO AMITRAZ: RELATÓRIO DE CASO E REVISÃO DA LITERATURA

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          Abstract

          La intoxicación por amitráz típicamente genera una variedad de síntomas tales como bradicardia e hipotensión, con colapso hemodinámico, que pueden ocasionar un riesgo para la vida; además se presenta depresión neurológica y respiratoria, todos estos explicados por una caída del tono simpático a nivel central y periférico. Los defectos en el ritmo cardiaco no son la característica mas sobresaliente de este tipo de intoxicación puesto que no se han descrito efectos cardiotóxicos directos ocasionados por este agente químico. En este artículo se reporta un caso en donde se observa defecto de la conducción cardiaca posterior a la ingestión de amitráz. La toxicidad cardiovascular se manifestó con hipotensión, bradicardia, y además incluyó un bloqueo aurículo-ventricular de II grado Mobitz I, que se resolvió espontáneamente después de 24 de monitorización.

          Translated abstract

          Amitraz poisoning typically produces a variety of symptoms, among others bradycardia and hypotension with hemodynamic collapse, that can be life-threatening; it can also show neurological and respiratory depression, all these explained by a fall in the sympathetic tone at central and peripheral level. Defects in heart rate are not the most outstanding characteristic of this sort of intoxication, since no direct cardio toxic effects have been proven to be caused by this chemical. This article reports a case where cardiac conduction defect is observed after ingestion of amitraz. Cardiovascular toxicity was manifested as hypotension, bradycardia, and also included was a second degree atrioventricular Mobitz I block, which spontaneously reverted after a 24 hour monitoring.

          Translated abstract

          A intoxicação por amitraz tipicamente produz uma variedade de sintomas como bradicardia e hipotensão arterial, com colapso hemodinâmico, que pode causar risco de vida; também apresentam depressão neurológica e respiratória, todos esses explicado por uma queda do tônus simpático, a nível central e periférico. Os defeitos da freqüência cardíaca não são a característica mais marcante de intoxicação, porém não tem sido descritos efeitos cardiotóxicos diretos causados por esta substância. Este artigo relata um caso que mostra um defeito de condução cardíaca após a ingestão de amitraz. A toxicidade cardiovascular foi manifestada como hipotensão, bradicardia, e também incluiu um bloqueio atrioventricular de segundo grau Mobitz I, que resolveu-se espontâneamente após 24 de monitorização.

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          Most cited references33

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          Mobbing and psychological terror at workplaces.

          H Leymann (1989)
          In recent years, the existence of a significant problem in workplaces has been documented in Sweden and other countries. It involves employees "ganging up" on a target employee and subjecting him or her to psychological harassment. This "mobbing" behavior results in severe psychological and occupational consequences for the victim. This phenomenon is described, its stages and consequences analyzed. An ongoing program of research and intervention that is currently being supported by the Swedish government is then considered.
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            Alpha-2 adrenoceptor agonists: defining the role in clinical anesthesia.

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              An unusual poisoning with the unusual pesticide amitraz.

              Amitraz, 1,5 di-(2,4-dimethylphenyl)-3-methyl-1,3,5-triaza-penta-1,4-diene, a formamidine pesticide, is used worldwide. It causes side-effects in animals that resemble those caused by pure alpha 2-adrenergic agonist drugs such as clonidine. Data on poisonings in humans are scanty. We report on a case of human poisoning with amitraz with typical signs of alpha 2-adrenoreceptor stimulation.
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                Author and article information

                Contributors
                Role: ND
                Role: ND
                Journal
                med
                Revista Med
                rev.fac.med
                Universidad Militar Nueva Granada. Facultad de Medicina (Bogotá )
                0121-5256
                December 2010
                : 18
                : 2
                : 228-234
                Affiliations
                [1 ] Hospital Universitario Hernando Moncaleano Perdomo Colombia
                [2 ] Hospital Universitario Hernando Moncaleano Perdomo Colombia
                Article
                S0121-52562010000200009
                df259356-ccc0-4f17-b12a-5dc12bf7c61a

                http://creativecommons.org/licenses/by/4.0/

                History
                Product

                SciELO Colombia

                Self URI (journal page): http://www.scielo.org.co/scielo.php?script=sci_serial&pid=0121-5256&lng=en
                Categories
                PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

                Public health
                amitraz,poisoning,atrioventricular block,intoxicação,bloqueio atrioventricular,amitráz,intoxicación,bloqueo aurículoventricular

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