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      Clinical Value of the Pitch of the Third Heart Sound in Ischemic Heart Disease

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          Abstract

          The study investigates the genesis of the third heart sound (S3) in ischemic heart disease based on a mass-spring model. In such a system, the natural frequency of vibration, Fn, depends on the elastic constant, k, and the mass, m, according to the following relationship: Fn = 1/2 π k/m. To identify the cardiac structures representing k and m, the correlations between the energy of the S3 spectrum and the echocardiographic parameters were searched for. The results are consistent with a model in which k is represented by the thickness of the left ventricle and m by its blood content. The k/m ratio emerges as an important determining factor of the acoustic quality of S3, and yields information on the dysfunction of the left ventricle in ischemic heart disease.

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          Author and article information

          Journal
          CRD
          Cardiology
          10.1159/issn.0008-6312
          Cardiology
          S. Karger AG
          0008-6312
          1421-9751
          1990
          1990
          12 November 2008
          : 77
          : 2
          : 86-92
          Affiliations
          aIstituto di Clinica Medica, Università di Ferrara; bDivisione Cardiologica, Ospedale di Legnago, Italia; cDepartment of Cardiology, KU Leuven, Belgium
          Article
          174588 Cardiology 1990;77:86–92
          10.1159/000174588
          2397490
          df9576ab-930c-449b-ab35-d46361334eeb
          © 1990 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 19 July 1989
          : 13 December 1989
          Page count
          Pages: 7
          Categories
          Original Paper

          General medicine,Neurology,Cardiovascular Medicine,Internal medicine,Nephrology
          Echocardiography,Spectral analysis,Third heart sound,Ischemic heart disease

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