Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head-to-Head Comparison with 13N-Ammonia PET.

Kaufmann, Philipp A.; Nkoulou, René; Fuchs, Tobias A; Pazhenkottil, Aju P.; Küest, Silke M.; Ghadri, Jelena R; Stehli, Julia; Fiechter, Michael; Herzog, Bernhard A; Gaemperli, Oliver; Buechel, Ronny R

doi:10.2967/jnumed.115.165498

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Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head-to-Head Comparison with 13N-Ammonia PET.

Author(s): Rene Nkoulou ¹ , Tobias A Fuchs ¹ , Aju P Pazhenkottil ¹ , Silke M Kuest ¹ , Jelena R Ghadri ¹ , Julia Stehli ¹ , Michael Fiechter ¹ , Bernhard A Herzog ¹ , Oliver Gaemperli ¹ , Ronny R Buechel ¹ , Philipp A Kaufmann ²

Publication date (Electronic): Dec 2016

Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Publisher: Society of Nuclear Medicine

Keywords: 13N-ammonia PET, cadmium zinc telluride (CZT) SPECT, myocardial blood flow (MBF), myocardial flow reserve (MFR)

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Abstract

Recent advances in SPECT technology including cadmium-zinc-telluride (CZT) semiconductor detector material may pave the way for absolute myocardial blood flow (MBF) measurements by SPECT. The aim of the present study was to compare K1 uptake rate constants as surrogates of absolute MBF and myocardial flow reserve index (MFRi) in humans as assessed with a CZT SPECT camera versus PET.

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Journal ID (iso-abbrev): J. Nucl. Med.

Title: Journal of nuclear medicine : official publication, Society of Nuclear Medicine

Publisher: Society of Nuclear Medicine

ISSN (Electronic): 1535-5667

ISSN (Print): 0161-5505

Publication date (Electronic): Dec 2016

Volume: 57

Issue: 12

Affiliations

[1 ] Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich and University of Zurich, Zurich, Switzerland.

[2 ] Department of Nuclear Medicine, Cardiac Imaging, University Hospital Zurich and University of Zurich, Zurich, Switzerland pak@usz.ch.

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Publisher Item ID: jnumed.115.165498

DOI: 10.2967/jnumed.115.165498

PubMed ID: 27363834

SO-VID: df99123d-f9eb-4253-ac00-6cc9183a2fc9

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Keywords: myocardial flow reserve (MFR),13N-ammonia PET,cadmium zinc telluride (CZT) SPECT,myocardial blood flow (MBF)

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Keywords: myocardial flow reserve (MFR), 13N-ammonia PET, cadmium zinc telluride (CZT) SPECT, myocardial blood flow (MBF)

Absolute Myocardial Blood Flow and Flow Reserve Assessed by Gated SPECT with Cadmium-Zinc-Telluride Detectors Using 99mTc-Tetrofosmin: Head-to-Head Comparison with 13N-Ammonia PET.

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