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      Refractive outcomes following cataract surgery in patients who have had myopic laser vision correction

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          Abstract

          Objective

          Prediction errors are increased among patients presenting for cataract surgery post laser vision correction (LVC) as biometric relationships are altered. We investigated the prediction errors of five formulae among these patients.

          Methods and analysis

          The intended refractive error was calculated as a sphero-cylinder and as a spherical equivalent for analysis. For determining the difference between the intended and postoperative refractive error, data were transformed into components of Long's formalism, before changing into sphero-cylinder notation. These differences in refractive errors were compared between the five formulae and to that of a control group using a Kruskal-Wallis test. An F-test was used to compare the variances of the difference distributions.

          Results

          22 eyes post LVC and 19 control eyes were included for analysis. Comparing both groups, there were significant differences in the postoperative refractive error (p=0.038). The differences between the intended and postoperative refractive error were greater in post LVC eyes than control eyes (p=0.012), irrespective of the calculation method for the intended refractive error (p<0.01). The mean difference between the intended and postoperative refractive error was relatively small, but its variance was significantly greater among post LVC eyes than control eyes (p<0.01). Among post LVC eyes, there were no significant differences between the mean intended target refraction and between the intended and postoperative refractive error using five biometry formulae (p=0.76).

          Conclusion

          Biometry calculations were less precise for patients who had LVC than patients without LVC. No particular biometry formula appears to be superior among patients post LVC.

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          Most cited references43

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          Power vectors: an application of Fourier analysis to the description and statistical analysis of refractive error.

          The description of sphero-cylinder lenses is approached from the viewpoint of Fourier analysis of the power profile. It is shown that the familiar sine-squared law leads naturally to a Fourier series representation with exactly three Fourier coefficients, representing the natural parameters of a thin lens. The constant term corresponds to the mean spherical equivalent (MSE) power, whereas the amplitude and phase of the harmonic correspond to the power and axis of a Jackson cross-cylinder (JCC) lens, respectively. Expressing the Fourier series in rectangular form leads to the representation of an arbitrary sphero-cylinder lens as the sum of a spherical lens and two cross-cylinders, one at axis 0 degree and the other at axis 45 degrees. The power of these three component lenses may be interpreted as (x,y,z) coordinates of a vector representation of the power profile. Advantages of this power vector representation of a sphero-cylinder lens for numerical and graphical analysis of optometric data are described for problems involving lens combinations, comparison of different lenses, and the statistical distribution of refractive errors.
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            Comparison of 9 intraocular lens power calculation formulas.

            To evaluate the accuracy of 9 intraocular lens (IOL) calculation formulas using 2 optical biometers.
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              Sources of error in intraocular lens power calculation.

              The hypothesis that the minimum error in predicted refraction after implantation of an intraocular lens (IOL) of calculated power is the sum of the random error in (1) the measurement of the axial length, (2) the measurement of the corneal power, and (3) the estimation of the pseudophakic anterior chamber depth (ACD) is proposed. Based on preoperative and postoperative biometry of 584 IOL implantations, 54% of the error was attributed to axial length errors, 8% to corneal power errors, and 38% to errors in the estimation of the postoperative ACD, when a fixed ACD was used in the IOL calculations. However, if the ACD was predicted according to a previously described regression method, the contribution of error from the ACD source was reduced to 22%, thereby reducing the total refractive prediction error from +/- 1.03 diopters (D) (+/- SD) to +/- 0.92 D (+/- SD). These predictions accord with clinical results.
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                Author and article information

                Journal
                BMJ Open Ophthalmol
                BMJ Open Ophthalmol
                bmjophth
                bmjophth
                BMJ Open Ophthalmology
                BMJ Publishing Group (BMA House, Tavistock Square, London, WC1H 9JR )
                2397-3269
                2019
                9 April 2019
                : 4
                : 1
                : e000242
                Affiliations
                [1 ] departmentSt. Paul's Eye Unit , Royal Liverpool University Hospital , Liverpool, UK
                [2 ] departmentInternational Centre for Eye Health , London School of Hygiene & Tropical Medicine , London, UK
                Author notes
                [Correspondence to ] Dr Chung Shen Chean; shen920815@ 123456hotmail.com
                Author information
                http://orcid.org/0000-0002-1625-4078
                Article
                bmjophth-2018-000242
                10.1136/bmjophth-2018-000242
                6528761
                31179392
                dfcfc9f8-57c5-4a3f-96fb-944ef3db1703
                © Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

                This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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                refractive surgery,cataract surgery,laser vision correction,biometry

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