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      The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction

      case-report

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          Abstract

          Purpose

          Erectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED has been in the past mistakenly considered a purely psycho-sexological symptom by patients and doctors. However, an ever-growing body of evidence supporting the role of several organic factors in the pathophysiological mechanisms underlying ED has been recognized.

          Methods

          The Italian Society of Andrology and Sexual Medicine (SIAMS) commissioned an expert task force involving several other National Societies to provide an updated guideline on the diagnosis and management of ED. Derived recommendations were based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system.

          Results

          Several evidence-based statements were released providing the necessary up-to-date guidance in the context of ED with organic and psychosexual comorbidities. Many of them were related to incorrect lifestyle habits suggesting how to associate pharmacotherapies and counseling, in a couple-centered approach. Having the oral therapy with phosphodiesterase type 5 inhibitors as the gold standard along with several other medical and surgical therapies, new therapeutic or controversial options were also discussed.

          Conclusions

          These are the first guidelines based on a multidisciplinary approach that involves the most important Societies related to the field of sexual medicine. This fruitful discussion allowed for a general agreement on several recommendations and suggestions to be reached, which can support all stakeholders in improving couple sexual satisfaction and overall general health.

          Supplementary Information

          The online version contains supplementary material available at 10.1007/s40618-023-02015-5.

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                Author and article information

                Contributors
                eajannini@gmail.com
                Journal
                J Endocrinol Invest
                J Endocrinol Invest
                Journal of Endocrinological Investigation
                Springer International Publishing (Cham )
                0391-4097
                1720-8386
                25 January 2023
                : 1-34
                Affiliations
                [1 ]GRID grid.414405.0, ISNI 0000 0004 1784 5501, Endocrinology Unit, Medical Department, , Maggiore-Bellaria Hospital, ; Azienda Usl, Bologna, Italy
                [2 ]GRID grid.10438.3e, ISNI 0000 0001 2178 8421, Chair of Internal Medicine, Department of Clinical and Experimental Medicine, , University of Messina, ; Messina, Italy
                [3 ]GRID grid.6530.0, ISNI 0000 0001 2300 0941, Section of Psychiatry, Department of Systems Medicine, , University of Rome Tor Vergata, ; Rome, Italy
                [4 ]GRID grid.417778.a, ISNI 0000 0001 0692 3437, IRCCS Fondazione Santa Lucia, ; Rome, Italy
                [5 ]GRID grid.5608.b, ISNI 0000 0004 1757 3470, Unit of Andrology and Reproductive Medicine, Department of Medicine, , University of Padova, ; Padua, Italy
                [6 ]GRID grid.7644.1, ISNI 0000 0001 0120 3326, Interdisciplinary Department of Medicine-Section of Internal Medicine, Geriatrics, Endocrinology and Rare Diseases, , University of Bari “Aldo Moro”, ; Bari, Italy
                [7 ]GRID grid.415208.a, ISNI 0000 0004 1785 3878, Santa Maria Hospital, GVM Care & Research, ; Bari, Italy
                [8 ]GRID grid.7841.a, Section of Food Science, Department of Experimental Medicine, , Sapienza University of Rome, ; Rome, Italy
                [9 ]GRID grid.7841.a, Section of Endocrinology, Department of Experimental Medicine, , Sapienza University of Rome, ; Rome, Italy
                [10 ]GRID grid.9841.4, ISNI 0000 0001 2200 8888, Division of Endocrinology and Metabolic Diseases, Department of Advanced Medical and Surgical Sciences, , University of Campania Luigi Vanvitelli, ; Naples, Italy
                [11 ]Diabetology and Endocrinology Unit, ASP #, Caltanissetta, Italy
                [12 ]Cardiology Unit, Città di Castello and Gubbio-GualdoTadino Hospitals, Azienda Usl Umbria 1, Gubbio, Italy
                [13 ]GRID grid.4691.a, ISNI 0000 0001 0790 385X, Dipartimento di Medicina Clinica e Chirurgia, Sezione di Endocrinologia, Unità di Andrologia e Medicina della Riproduzione e della Sessualità Maschile e Femminile, , Università Federico II di Napoli, ; Naples, Italy
                [14 ]GRID grid.4691.a, ISNI 0000 0001 0790 385X, Staff of UNESCO Chair for Health Education and Sustainable Development, Federico II University, ; Naples, Italy
                [15 ]GRID grid.7548.e, ISNI 0000000121697570, Department of Biomedical, Metabolic and Neural Sciences, , University of Modena and Reggio Emilia, ; Modena, Italy
                [16 ]GRID grid.413009.f, Department of Biomedicine and Prevention, , Policlinico Tor Vergata, ; Rome, Italy
                [17 ]Diabetology Unit, ASP Reggio Calabria, Reggio Calabria, Italy
                [18 ]GRID grid.8404.8, ISNI 0000 0004 1757 2304, Endocrinology Unit, Department of Experimental, Clinical and Biomedical Sciences, , University of Florence, ; Florence, Italy
                [19 ]GRID grid.6530.0, ISNI 0000 0001 2300 0941, Chair of Endocrinology and Sexual Medicine (ENDOSEX), Department of Systems Medicine, , University of Rome Tor Vergata, ; E Tower South Floor 4, Room E413, Via Montpellier 1, 00133 Rome, Italy
                Author information
                http://orcid.org/0000-0002-5874-039X
                Article
                2015
                10.1007/s40618-023-02015-5
                9876440
                36698034
                dff52dfe-9d3d-4d93-80ba-cd21d02fc6ab
                © The Author(s), under exclusive licence to Italian Society of Endocrinology (SIE) 2023

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

                History
                : 16 October 2022
                : 16 January 2023
                Categories
                Consensus Statement

                erectile dysfunction,premature ejaculation,sexual desire,obesity,testosterone,phosphodiesterase type 5 inhibitors

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