15
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Detecting Dementia Through Interactive Computer Avatars

      research-article

      Read this article at

      ScienceOpenPublisherPMC
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          This paper proposes a new approach to automatically detect dementia. Even though some works have detected dementia from speech and language attributes, most have applied detection using picture descriptions, narratives, and cognitive tasks. In this paper, we propose a new computer avatar with spoken dialog functionalities that produces spoken queries based on the mini-mental state examination, the Wechsler memory scale-revised, and other related neuropsychological questions. We recorded the interactive data of spoken dialogues from 29 participants (14 dementia and 15 healthy controls) and extracted various audiovisual features. We tried to predict dementia using audiovisual features and two machine learning algorithms (support vector machines and logistic regression). Here, we show that the support vector machines outperformed logistic regression, and by using the extracted features they classified the participants into two groups with 0.93 detection performance, as measured by the areas under the receiver operating characteristic curve. We also newly identified some contributing features, e.g., gap before speaking, the variations of fundamental frequency, voice quality, and the ratio of smiling. We concluded that our system has the potential to detect dementia through spoken dialog systems and that the system can assist health care workers. In addition, these findings could help medical personnel detect signs of dementia.

          Abstract

          Dialogue procedures and subtitles. Japanese sentences and subtitles are translated into English (Sub). The system includes six continuous dialogue procedures.

          Related collections

          Most cited references31

          • Record: found
          • Abstract: found
          • Article: not found

          Investigation of the single case in neuropsychology: confidence limits on the abnormality of test scores and test score differences.

          Neuropsychologists often need to estimate the abnormality of an individual patient's test score, or test score discrepancies, when the normative or control sample against which the patient is compared is modest in size. Crawford and Howell [The Clinical Neuropsychologist 12 (1998) 482] and Crawford et al. [Journal of Clinical and Experimental Neuropsychology 20 (1998) 898] presented methods for obtaining point estimates of the abnormality of test scores and test score discrepancies in this situation. In the present study, we extend this work by developing methods of setting confidence limits on the estimates of abnormality. Although these limits can be used with data from normative or control samples of any size, they will be most useful when the sample sizes are modest. We also develop a method for obtaining point estimates and confidence limits on the abnormality of a discrepancy between a patient's mean score on k-tests and a test entering into that mean. Computer programs that implement the formulae for the confidence limits (and point estimates) are described and made available.
            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Social signal processing: Survey of an emerging domain

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Language performance in Alzheimer's disease and mild cognitive impairment: a comparative review.

              Mild cognitive impairment (MCI) manifests as memory impairment in the absence of dementia and progresses to Alzheimer's disease (AD) at a rate of around 15% per annum, versus 1-2% in the general population. It thus constitutes a primary target for investigation of early markers of AD. Language deficits occur early in AD, and performance on verbal tasks is an important diagnostic criterion for both AD and MCI. We review language performance in MCI, compare these findings to those seen in AD, and identify the primary issues in understanding language performance in MCI and selecting tasks with diagnostic and prognostic value.
                Bookmark

                Author and article information

                Contributors
                Journal
                IEEE J Transl Eng Health Med
                IEEE J Transl Eng Health Med
                0063400
                JTEHM
                IJTEBN
                IEEE Journal of Translational Engineering in Health and Medicine
                IEEE
                2168-2372
                2017
                15 September 2017
                : 5
                : 2200111
                Affiliations
                [1]divisionGraduate School of Information Science, institutionNara Institute of Science and Technology; Nara630-0101Japan
                [2]divisionHealth and Counseling Center, institutionOsaka University; Osaka560-0043Japan
                [3]divisionGraduate School of Engineering, institutionToyota Technological Institute; Nagoya468-8511Japan
                [4]departmentDepartment of Psychiatry, divisionGraduate School of Medicine, institutionOsaka University; Osaka565-0871Japan
                Author notes
                Article
                2200111
                10.1109/JTEHM.2017.2752152
                5630006
                29018636
                dffe2c1e-476f-4474-8d38-67dcbf1be29c
                2168-2372 © 2017 IEEE. Translations and content mining are permitted for academic research only. Personal use is also permitted, but republication/redistribution requires IEEE permission. See http://www.ieee.org/publications_standards/publications/rights/index.html for more information.
                History
                : 26 April 2017
                : 13 July 2017
                : 25 August 2017
                : 01 September 2017
                : 29 September 2017
                Page count
                Figures: 2, Tables: 3, Equations: 23, References: 62, Pages: 11
                Funding
                Funded by: JSPS KAKENHI, fundref 10.13039/501100001691;
                Award ID: JP17H06101
                Award ID: JP16K16172
                Funded by: Yanmar Innovation Lab. 2112;
                This work was supported in part by JSPS KAKENHI under Grant JP17H06101 and Grant JP16K16172 and the Yanmar Innovation Lab. 2112.
                Categories
                Article

                dementia,spoken dialogue,computer avatars,alzheimer’s disease,mmse

                Comments

                Comment on this article